Sodium chloride Disease Interactions
There are 2 disease interactions with sodium chloride.
Sodium salts (applies to sodium chloride) sodium/water imbalance
Major Potential Hazard, High plausibility. Applicable conditions: Fluid Retention, Congestive Heart Failure, Hypokalemia
Sodium chloride can induce sodium and water retention and result in hypernatremia, hypokalemia, edema and aggravation of congestive heart failure. Therapy with sodium- containing agents should be administered with extreme caution, if at all, in patients with congestive heart failure, severe renal insufficiency, and in clinical states where there is edema with sodium retention. Clinical monitoring of acid/base balance and electrolytes prior to, during, a following completion of therapy with sodium- containing agents is recommended.
Sodium chloride (applies to sodium chloride) acidosis
Moderate Potential Hazard, Moderate plausibility.
Administration of excessive amounts of sodium chloride can increase chloride concentrations and cause a loss of bicarbonate that results in metabolic acidosis. Clinical monitoring of acid/base balance and electrolyte concentrations is recommended.
Sodium chloride drug interactions
There are 2 drug interactions with sodium chloride.
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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