KedRAB Disease Interactions
There are 2 disease interactions with KedRAB (rabies immune globulin, human).
Rabies (applies to KedRAB) antibody response
Major Potential Hazard, High plausibility. Applicable conditions: Immunodeficiency
Patients with primary or acquired deficient/impaired immune response (immunosuppressive therapy, genetic, splenic dysfunction, immunodeficiency disorders) may have reduced antibody response to immunizations. Deferral of immunosuppressive therapy may be considered pending completion of post-exposure therapy unless essential for treatment of other conditions.
References (1)
- (2001) "Product Information. Bayrab (rabies immune globulin, human)." Bayer
Vaccines (applies to KedRAB) IM injection
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Thrombocytopenia, Thrombocytopathy, Coagulation Defect
In patients with thrombocytopenia or coagulation disorders, IM injections may produce bleeding and hematomas. Patients with a platelet count less than 50,000/mm3 are at an increased risk. Caution is advised if the vaccine (e.g., plague vaccine; hepatitis A and B vaccines; aluminum-adsorbed DTaP, DTP, DT, or Td) must be administered IM. The risk of bleeding may be minimized by vaccination immediately after the administration of replacement factor, use of a 23-gauge (or smaller) needle, and immediate application of direct pressure to the vaccination site for at least 2 minutes.
References (10)
- (2001) "Product Information. Plague Vaccine (plague vaccine)." Greer Laboratories Inc
- "Product Information. Cholera Vaccine (cholera vaccine)." Wyeth-Ayerst Laboratories
- "Product Information. Havrix (HepA) (hepatitis A adult vaccine)." SmithKline Beecham
- (2022) "Product Information. Engerix-B (HepB) (hepatitis B adult vaccine)." Apothecon Inc
- (2005) "Product Information. Menactra (meningococcal conjugate vaccine)." sanofi pasteur
- (2022) "Product Information. ActHIB (Hib) (haemophilus b conjugate (PRP-T) vaccine)." sanofi pasteur
- (2010) "Product Information. Imogam Rabies-HT (rabies immune globulin, human)." sanofi pasteur
- (2015) "Product Information. Hyperrab S/D (rabies immune globulin, human)." Grifols Therapeutics
- (2022) "Product Information. Bexsero (meningococcal group B vaccine)." Novartis Vaccines & Diagnostics Inc
- (2024) "Product Information. Mresvia Prefilled Syringe (cvx 326) (RSV mRNA vaccine (cvx 326))." Moderna US, Inc
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KedRAB drug interactions
There are 25 drug interactions with KedRAB (rabies immune globulin, human).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.