KedRAB Side Effects

Generic name: rabies immune globulin, human

Medically reviewed by Drugs.com. Last updated on Jan 19, 2025.

Note: This document provides detailed information about KedRAB.

Applies to rabies immune globulin, human: intramuscular solution Side Effects associated with rabies immune globulin, human. Some dosage forms listed on this page may not apply specifically to the brand name KedRAB.

Applies to rabies immune globulin, human: intramuscular solution.

Precautions

It is very important that your doctor check you closely to make sure that this medicine is working properly. Blood tests are needed to check for unwanted effects.

This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them, although the risk is low. Human donors and donated blood are both tested for viruses to keep the transmission risk low. Talk with your doctor if you have concerns about this risk.

While you are being treated with rabies immune globulin, do not have any immunizations (vaccinations) without your doctor's approval. You should not receive measles vaccine within 4 months after receiving rabies immune globulin. You should not also receive other live virus vaccines (eg, mumps, polio, rubella) within 3 months after receiving this medicine.

This medicine may cause serious allergic reactions, including anaphylaxis. This can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving this medicine.

This medicine may increase your risk of developing blood problems, including blood clots or hemolysis (breakdown of red blood cells). Check with your doctor right away if you have swelling and pain in your arms, legs, or stomach, chest pain, shortness of breath, loss of sensation, confusion, problems with muscle control or speech, stomach or back pain, dark urine, decreased urination, fever, tiredness, or yellow eyes or skin.

Serious side effects of KedRAB

Along with its needed effects, rabies immune globulin, human (the active ingredient contained in KedRAB) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking rabies immune globulin, human:

Other side effects of KedRAB

Some side effects of rabies immune globulin, human may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to rabies immune globulin, human: intramuscular solution.

General adverse events

The most common adverse events were injection site and skin reactions.^[Ref]

Local

• Rare (less than 0.1%): Injection site: swelling, pain, erythema, induration, warmth, pruritus, rash
• Frequency not reported: Discomfort at injection site, soreness at injection site^[Ref]

Dermatologic

• Rare (less than 0.1%): Skin reaction, erythema, pruritus, skin rash
• Frequency not reported: Angioneurotic edema, bruising^[Ref]

Hypersensitivity

• Rare (less than 0.1%): Hypersensitivity, anaphylactic shock, allergic type reactions^[Ref]

Other

• Rare (less than 0.1%): Fever, malaise, chill, fatigue, influenza like illness
• Frequency not reported: Mild temperature elevations, disabling pain that limited motion^[Ref]

Renal

• Rare (less than 0.1%): Nephrotic syndrome^[Ref]

Cardiovascular

• Rare (less than 0.1%): Tachycardia, hypotension^[Ref]

Musculoskeletal

• Rare (less than 0.1%): Arthralgia
• Frequency not reported: Compartment syndrome, infiltration of wounds^[Ref]

Gastrointestinal

• Rare (less than 0.1%): Nausea, vomiting^[Ref]

Nervous system

• Rare (less than 0.1%): Headache^[Ref]

Immunologic

• Frequency not reported: Sensitization to repeated injections^[Ref]

See also:

Further information

KedRAB side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer