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Phenoxybenzamine Disease Interactions

There is 1 disease interaction with phenoxybenzamine:


Phenoxybenzamine (Includes phenoxybenzamine) ↔ cardiovascular dysfunction

Severe Potential Hazard, High plausibility. Applies to: Cerebral Vascular Disorder, Ischemic Heart Disease, Congestive Heart Failure

The use of phenoxybenzamine is contraindicated when a decrease in blood pressure may be undesirable, such as in patients with marked cerebrovascular or coronary insufficiency in whom ischemia may be aggravated. Also, phenoxybenzamine- induced reflex tachycardia can precipitate frank congestive heart failure (CHF) and angina in patients with compensated CHF or coronary artery disease. Phenoxybenzamine should be used with caution under such circumstances.


  1. "Product Information. Dibenzyline Capsules (phenoxybenzamine)." SmithKline Beecham, Philadelphia, PA.

Phenoxybenzamine drug interactions

There are 168 drug interactions with phenoxybenzamine

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.