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Natpara (parathyroid hormone) Disease Interactions

There are 2 disease interactions with Natpara (parathyroid hormone):


Parathyroid Hormone/Analogs (Includes Natpara) ↔ Malignancy

Severe Potential Hazard, Moderate plausibility

Applies to: Paget's Disease, Neoplasm of Bone

Parathyroid hormone and its analogs should not be used in patients who are at increased baseline risk for osteosarcoma. These agents should only be used if the potential benefits are considered to outweigh the potential risks. Monitor these patients according to clinical guidelines. Patients with bone metastases or a history of skeletal malignancies should not be treated with these agents.


Parathyroid Hormone (Includes Natpara) ↔ Renal Impairment

Moderate Potential Hazard, Moderate plausibility

Applies to: Renal Dysfunction

Parathyroid hormone is eliminated by the kidney and maximum drug levels increased with renal impairment. No dose adjustment is recommended in patients with mild to moderate renal impairment. No studies have been conducted in patients with severe renal impairment or in renal impairment patients on dialysis. Care and close monitoring should be exercised when using this agent in patients with severe renal impairment or on dialysis.

Natpara (parathyroid hormone) drug Interactions

There are 7 drug interactions with Natpara (parathyroid hormone)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

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