Skip to main content

Pancrelipase Disease Interactions

There is 1 disease interaction with pancrelipase.


Pancrelipase (applies to pancrelipase) hyperuricemia

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Gout, Renal Dysfunction

Porcine-derived pancreatic enzyme products contain purines that may increase blood uric acid levels. Extremely high dosages of exogenous pancreatic enzymes have also been associated with hyperuricosuria and hyperuricemia. Therapy with pancrelipase should be administered cautiously in patients with preexisting hyperuricemia, gout, or renal impairment. Monitoring of serum uric acid levels is recommended.


  1. (2001) "Product Information. Viokase (pancrelipase)." Wyeth-Ayerst Laboratories
  2. (2022) "Product Information. Ku-Zyme (pancrelipase)." Schwarz Pharma
  3. (2001) "Product Information. Zymase (pancrelipase)." Organon
  4. (2001) "Product Information. Cotazym (pancrelipase)." Organon
  5. (2001) "Product Information. Cotazym-S (pancrelipase)." Organon
  6. (2001) "Product Information. Pancrease (pancrelipase)." McNeil Pharmaceutical
  7. (2022) "Product Information. Pancrease (pancrelipase)." Apothecon Inc
  8. (2001) "Product Information. Ultrase (pancrelipase)." Scandipharm Inc
  9. "Product Information. Ultrase MT 12 (pancrelipase)." Scandipharm Inc
  10. (2001) "Product Information. Creon 5 (pancrelipase)." Solvay Pharmaceuticals Inc
  11. (2001) "Product Information. Creon 10 (pancrelipase)." Solvay Pharmaceuticals Inc
  12. (2001) "Product Information. Creon 20 (pancrelipase)." Solvay Pharmaceuticals Inc
View all 12 references

Pancrelipase drug interactions

There are 26 drug interactions with pancrelipase.

Pancrelipase alcohol/food interactions

There is 1 alcohol/food interaction with pancrelipase.

Report options

QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.