Skip to main content

Zenpep Disease Interactions

There is 1 disease interaction with Zenpep (pancrelipase).


Pancrelipase (applies to Zenpep) hyperuricemia

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Gout, Renal Dysfunction

Porcine-derived pancreatic enzyme products contain purines that may increase blood uric acid levels. Extremely high dosages of exogenous pancreatic enzymes have also been associated with hyperuricosuria and hyperuricemia. Therapy with pancrelipase should be administered cautiously in patients with preexisting hyperuricemia, gout, or renal impairment. Monitoring of serum uric acid levels is recommended.


  1. "Product Information. Viokase (pancrelipase)." Wyeth-Ayerst Laboratories (2001):
  2. "Product Information. Ku-Zyme (pancrelipase)." Schwarz Pharma (2022):
  3. "Product Information. Zymase (pancrelipase)." Organon (2001):
  4. "Product Information. Cotazym (pancrelipase)." Organon (2001):
  5. "Product Information. Cotazym-S (pancrelipase)." Organon (2001):
  6. "Product Information. Pancrease (pancrelipase)." McNeil Pharmaceutical (2001):
  7. "Product Information. Pancrease (pancrelipase)." Apothecon Inc (2022):
  8. "Product Information. Ultrase (pancrelipase)." Scandipharm Inc (2001):
  9. "Product Information. Ultrase MT 12 (pancrelipase)." Scandipharm Inc
  10. "Product Information. Creon 5 (pancrelipase)." Solvay Pharmaceuticals Inc (2001):
  11. "Product Information. Creon 10 (pancrelipase)." Solvay Pharmaceuticals Inc (2001):
  12. "Product Information. Creon 20 (pancrelipase)." Solvay Pharmaceuticals Inc (2001):
View all 12 references

Zenpep drug interactions

There are 25 drug interactions with Zenpep (pancrelipase).

Zenpep alcohol/food interactions

There is 1 alcohol/food interaction with Zenpep (pancrelipase).

Report options

Share by QR Code
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.