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Nirogacestat Disease Interactions

There is 1 disease interaction with nirogacestat.

Moderate

Nirogacestat (applies to nirogacestat) liver dysfunction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Nirogacestat should be used with caution in patients with severe liver dysfunction as there is insufficient data available to characterize the pharmacokinetics of this drug in this population.

References

  1. (2023) "Product Information. Ogsiveo (nirogacestat)." SpringWorks Therapeutics, Inc.

Nirogacestat drug interactions

There are 314 drug interactions with nirogacestat.

Nirogacestat alcohol/food interactions

There is 1 alcohol/food interaction with nirogacestat.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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