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Macimorelin Disease Interactions

There is 1 disease interaction with macimorelin.

Moderate

Macimorelin (applies to macimorelin) arrhythmias

Moderate Potential Hazard, Moderate plausibility.

Macimorelin can cause an increase of about 11 msec in the corrected QT (QTc) interval that can lead to development of torsade de pointes-type ventricular tachycardia. It is recommended to avoid the concomitant use of macimorelin with drugs that are known to prolong the QT interval. Care should be exercised when using this agent in patients with arrhythmias or conduction disorders.

References

  1. (2018) "Product Information. Macrilen (macimorelin)." Aeterna Zentaris

Macimorelin drug interactions

There are 343 drug interactions with macimorelin.

Macimorelin alcohol/food interactions

There is 1 alcohol/food interaction with macimorelin.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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