Denovo Disease Interactions
There is 1 disease interaction with Denovo (l-methylfolate).
L-methylfolate (applies to Denovo) bipolar disorder
Moderate Potential Hazard, Moderate plausibility.
L-methylfolate should be used with caution in patients with a history of bipolar disorder. Patients with depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder since mood elevation in this population is possible.
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Denovo drug interactions
There are 25 drug interactions with Denovo (l-methylfolate).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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