Camptosar (irinotecan) Disease Interactions
There is 1 disease interaction with Camptosar (irinotecan):
Irinotecan (Includes Camptosar) ↔ myelosuppression
Severe Potential Hazard, High plausibility. Applies to: Bleeding, Bone Marrow Depression/Low Blood Counts
Irinotecan induces myelosuppression, causing leukopenia and anemia. Deaths due to sepsis following severe neutropenia have been reported in patients treated with irinotecan. Hold irinotecan if neutropenic fever occurs or if the absolute neutrophil count drops <1000/mm3. After recovery to an absolute neutrophil count =1000/mm3, subsequent doses of irinotecan should be reduced. Therapy with irinotecan should be administered cautiously in patients who have received previous irradiation therapy. Patients should be instructed to immediately report any signs or symptoms suggesting bone marrow suppression such as fever, sore throat, local infection, or bleeding. Close clinical monitoring of hematopoietic function is recommended.
- "Product Information. Camptosar (irinotecan)." Pharmacia and Upjohn, Kalamazoo, MI.
Camptosar (irinotecan) drug interactions
There are 433 drug interactions with Camptosar (irinotecan)
More about Camptosar (irinotecan)
- Camptosar Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- 1 Review
- Generic Availability
- Drug class: miscellaneous antineoplastics
- FDA Alerts (2)
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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