Skysona Disease Interactions
There are 4 disease interactions with Skysona (elivaldogene autotemcel).
Elivaldogene autotemcel (applies to Skysona) infections
Major Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral
Severe infections, including fatal infections have occurred in patients after infusion with elivaldogene autotemcel. Patients should be monitored for infection before and during treatment, and prophylactic antimicrobials may need to be administered according to clinical guidelines. Administration of elivaldogene autotemcel should be avoided in patients with active infections.
Elivaldogene autotemcel (applies to Skysona) HIV
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: HIV Infection
Elivaldogene autotemcel has not been studied in patients with HIV. A negative serology test for HIV is necessary before the collection of cells, to ensure acceptance of apheresis material for elivaldogene autotemcel manufacturing. Material for patients with a positive HIV test, will not be accepted for manufacturing.
Elivaldogene autotemcel (applies to Skysona) hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Elivaldogene autotemcel has not been studied in patients with hepatic impairment. Patients should be assessed for hepatic impairment to ensure that hematopoietic stem cell (HSC) transplantation is appropriate.
Elivaldogene autotemcel (applies to Skysona) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Elivaldogene autotemcel has not been studied in patients with renal impairment. Patients should be assessed for renal impairment, to ensure that hematopoietic stem cell (HSC) transplantation is appropriate.
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Skysona drug interactions
There are 132 drug interactions with Skysona (elivaldogene autotemcel).
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- FDA approval history
- Drug class: miscellaneous uncategorized agents
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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