Elafibranor Disease Interactions
There is 1 disease interaction with elafibranor.
Elafibranor (applies to elafibranor) liver dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
The safety and efficacy of elafibranor have not been established in patients with decompensated cirrhosis. Use of elafibranor is not recommended in patients who have or develop decompensated cirrhosis (e.g., ascites, variceal bleeding, hepatic encephalopathy). Monitor patients with cirrhosis for evidence of decompensation. Consider discontinuing elafibranor if the patient progresses to moderate or severe liver dysfunction (Child-Pugh B or C). No dose adjustment is recommended in patients with mild to moderate liver dysfunction (Child-Pugh A).
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Elafibranor drug interactions
There are 244 drug interactions with elafibranor.
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- Drug class: miscellaneous metabolic agents
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
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Livdelzi
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Ocaliva
Ocaliva may be used to treat primary biliary cholangitis (PBC) in adults without cirrhosis or with ...
Iqirvo
Iqirvo (elafibranor) is used to treat primary biliary cholangitis (PBC) in combination with ...
Reltone
Reltone is used for gallbladder disease, primary biliary cholangitis
Obeticholic acid
Obeticholic acid (brand name Ocaliva) may be used to treat primary biliary cholangitis (PBC) in ...
Seladelpar
Seladelpar is used to treat primary biliary cholangitis (PBC) in adults. It is a once-daily capsule ...
Further information
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