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Prepidil (dinoprostone topical) Disease Interactions

There are 3 disease interactions with Prepidil (dinoprostone topical):

Moderate

Dinoprostone Topical (Includes Prepidil) ↔ Asthma

Moderate Potential Hazard, Moderate plausibility

Applies to: Asthma

The use of dinoprostone may be associated with bronchospasm, decreased pulmonary blood flow, and/or increased pulmonary arterial pressure. Dinoprostone induces contraction of smooth muscle, including smooth muscle of the respiratory tract. Therapy with dinoprostone should be administered cautiously in patients with asthma, or history of childhood asthma, even in the absence of asthma attacks in adulthood.

References

  1. "Product Information. Prepidil (dinoprostone topical)" Pharmacia and Upjohn, Kalamazoo, MI.
Moderate

Dinoprostone Topical (Includes Prepidil) ↔ Hypotension

Moderate Potential Hazard, High plausibility

Applies to: Hypotension

Therapy with dinoprostone should be administered cautiously in patients with a history of hypotension.

References

  1. "Product Information. Prepidil (dinoprostone topical)" Pharmacia and Upjohn, Kalamazoo, MI.
Moderate

Dinoprostone Topical Glaucoma

Moderate Potential Hazard, Moderate plausibility

Applies to: Glaucoma/Intraocular Hypertension

Caution should be exercised when administering dinoprostone topical in patients with a history of glaucoma.

References

  1. "Product Information. Prepidil (dinoprostone topical)" Pharmacia and Upjohn, Kalamazoo, MI.

Prepidil (dinoprostone topical) drug Interactions

There are 7 drug interactions with Prepidil (dinoprostone topical)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

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