Prepidil Disease Interactions
There are 3 disease interactions with Prepidil (dinoprostone topical).
Dinoprostone topical (applies to Prepidil) asthma
Moderate Potential Hazard, Moderate plausibility.
The use of dinoprostone may be associated with bronchospasm, decreased pulmonary blood flow, and/or increased pulmonary arterial pressure. Dinoprostone induces contraction of smooth muscle, including smooth muscle of the respiratory tract. Therapy with dinoprostone should be administered cautiously in patients with asthma, or history of childhood asthma, even in the absence of asthma attacks in adulthood.
Dinoprostone topical (applies to Prepidil) hypotension
Moderate Potential Hazard, High plausibility.
Therapy with dinoprostone should be administered cautiously in patients with a history of hypotension.
Dinoprostone topical glaucoma
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Glaucoma/Intraocular Hypertension
Caution should be exercised when administering dinoprostone topical in patients with a history of glaucoma.
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Prepidil drug interactions
There are 6 drug interactions with Prepidil (dinoprostone topical).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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