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Dextran-HM (dextran, high molecular weight) Disease Interactions

There are 4 disease interactions with Dextran-HM (dextran, high molecular weight):

Major

Dextran (applies to Dextran-HM) cardiac failure

Major Potential Hazard, Moderate plausibility. Applicable conditions: Heart Disease

Low molecular weight and high molecular weight dextran is contraindicated in patients with marked cardiac decompensation.

Major

Dextran (applies to Dextran-HM) hemostatic defects

Major Potential Hazard, Moderate plausibility. Applicable conditions: Bleeding Associated with Coagulation Defect, Thrombocytopenia

The use of dextran is contraindicated in patients with marked hemostatic defects of all types (thrombocytopenia, hypofibrinogenemia, etc.) including those caused by drugs such as heparin, warfarin, etc.

Major

Dextran (applies to Dextran-HM) renal impairment

Major Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Low molecular and high molecular weight dextran are contraindicated in patients with renal disease with severe oliguria or anuria.

Moderate

Dextran (applies to Dextran-HM) bleeding

Moderate Potential Hazard, Moderate plausibility.

Caution should be employed when using dextran (low and high molecular weight) in patients with active hemorrhage as the resulting increase in perfusion pressure and improved microcirculatory flow may result in additional blood loss.

Dextran-HM (dextran, high molecular weight) drug interactions

There are 26 drug interactions with Dextran-HM (dextran, high molecular weight)

More about Dextran-HM (dextran, high molecular weight)

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.