Cetrorelix Disease Interactions
There are 3 disease interactions with cetrorelix.
Cetrorelix (applies to cetrorelix) severe allergies
Major Potential Hazard, Moderate plausibility.
Treatment with cetrorelix is not advised in women with severe allergic conditions. Cases of hypersensitivity reactions, including anaphylactoid reactions with the first dose, have been reported during postmarketing surveillance, and a rare case of a severe anaphylactic reaction was observed after 7 months of treatment. Special care should be taken in women with signs and symptoms of active allergic conditions or known history of allergic predisposition.
Cetrorelix (applies to cetrorelix) severe renal impairment
Major Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
The use of cetrorelix is contraindicated in patients with severe renal impairment. Additionally, pharmacokinetic investigations have not been performed in subjects with impaired renal function.
Cetrorelix (applies to cetrorelix) hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Pharmacokinetic investigations have not been performed in subjects with impaired liver function. Caution is advised if used in these patients.
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Cetrorelix drug interactions
There are 2 drug interactions with cetrorelix.
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- Drug class: gonadotropin-releasing hormone antagonists
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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