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Cetrorelix Disease Interactions

There are 3 disease interactions with cetrorelix:

Major

Cetrorelix (applies to cetrorelix) severe allergies

Major Potential Hazard, Moderate plausibility.

Treatment with cetrorelix is not advised in women with severe allergic conditions. Cases of hypersensitivity reactions, including anaphylactoid reactions with the first dose, have been reported during postmarketing surveillance, and a rare case of a severe anaphylactic reaction was observed after 7 months of treatment. Special care should be taken in women with signs and symptoms of active allergic conditions or known history of allergic predisposition.

Major

Cetrorelix (applies to cetrorelix) severe renal impairment

Major Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

The use of cetrorelix is contraindicated in patients with severe renal impairment. Additionally, pharmacokinetic investigations have not been performed in subjects with impaired renal function.

Moderate

Cetrorelix (applies to cetrorelix) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Pharmacokinetic investigations have not been performed in subjects with impaired liver function. Caution is advised if used in these patients.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.