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Cetrorelix Side Effects

For the Consumer

Applies to cetrorelix: subcutaneous powder for solution

Along with its needed effects, cetrorelix may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cetrorelix:

Less common
  • Abdominal or stomach pain
  • continuing or severe nausea, vomiting or diarrhea
  • decreased amount of urine
  • feeling of indigestion
  • moderate to severe bloating
  • pelvic pain, severe
  • rapid weight gain
  • shortness of breath
  • swelling of lower legs

Some side effects of cetrorelix may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Headache
  • injection site bruising, itching, swelling, or redness
  • nausea

For Healthcare Professionals

Applies to cetrorelix: subcutaneous powder for injection

Endocrine

Common (1% to 10%): Mild to moderate ovarian hyperstimulation syndrome (OHSS) (WHO grade I or II)
Uncommon (0.1% to 1%): Severe ovarian hyperstimulation syndrome (WHO grade III)[Ref]

Gastrointestinal

Very common (10% or more): Nausea (12%)[Ref]

General

The most commonly reported side effects were local injection site reactions such as erythema, swelling, and pruritus that were usually transient in nature and mild in intensity.[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Systemic allergic/pseudo-allergic reactions including life-threatening anaphylaxis[Ref]

Local

Common (1% to 10%): Redness, erythema, bruising, itching, swelling, pruritus (at the injection site)[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Cetrotide (cetrorelix)" Asta Medica Inc, Tewksbury, MA.

Some side effects of cetrorelix may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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