Brexucabtagene autoleucel Disease Interactions
There is 1 disease interaction with brexucabtagene autoleucel.
Brexucabtagene autoleucel (applies to brexucabtagene autoleucel) infections
Major Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral
Brexucabtagene autoleucel has caused severe or life-threatening infections, including hepatitis B reactivation and fatal opportunistic infections in immunosuppressed patients. Screening for hepatitis B and C virus, and for human immunodeficiency virus (HIV) in accordance with clinical guidelines should be performed before collection of cells for manufacturing. Monitor patients for signs and symptoms of infection before and after infusion, administer prophylactic antimicrobials as needed, and treat promptly and appropriately any infection.
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Brexucabtagene autoleucel drug interactions
There are 308 drug interactions with brexucabtagene autoleucel.
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- During pregnancy
- Drug class: miscellaneous antineoplastics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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