Aflibercept ophthalmic Disease Interactions
There is 1 disease interaction with aflibercept ophthalmic:
Intravitreal Injections (Includes Aflibercept ophthalmic) ↔ Ocular Infections
Severe Potential Hazard, High plausibility
Applies to: Ocular Infection, Uveitis, Orbital Infection, Infectious Endophthalmitis, Infectious Optic Neuritis
Intravitreal administration, including those with aflibercept, pegaptanib, and ranibizumab is contraindicated in patients with active intraocular inflammation or ocular/periocular infections, since endophthalmitis can occur following the use of these injections. Patients should be advised to seek immediate medical attention from an ophthalmologist if the eye becomes red, photosensitive or painful, or if there is a change in vision in the days following the injection.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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