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Acetic acid / antipyrine / benzocaine / polycosanol otic Disease Interactions

There is 1 disease interaction with acetic acid / antipyrine / benzocaine / polycosanol otic:

Major

Otic agents (Includes acetic acid/antipyrine/benzocaine/polycosanol otic) ↔ perforated tympanic membrane

Severe Potential Hazard, High plausibility. Applies to: Perforated Tympanic Membrane, Chronic Otitis Media, Perforated Tympanic Membrane, Chronic Otitis Media, Perforated Tympanic Membrane, Chronic Otitis Media

The use of medications that are intended for the treatment of otitis externa or other conditions of the external ear canal should generally be avoided, or otherwise approached with caution, in patients with a perforated tympanic membrane due to the risk of toxicity from medication that may get into the middle ear. Caution is also advised in patients with longstanding, chronic otitis media because of the possibility of a perforated tympanic membrane in such patients.

References

  1. Behrman R, Kliegman R, Arvin A, Nelson W, eds. "Nelson Textbook of Pediatrics. 15th ed." Philadelphia, PA: W.B. Saunders Company (1996):
  2. "Multum Information Services, Inc. Expert Review Panel"

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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