Generic Name: etelcalcetide (Intravenous route)
Medically reviewed by Drugs.com. Last updated on Apr 5, 2019.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Endocrine-Metabolic Agent
Pharmacologic Class: Calcimimetic
Uses for Parsabiv
Etelcalcetide injection is used to used to treat secondary hyperparathyroidism in patients with chronic kidney disease who are on dialysis. Hyperparathyroidism is a condition that is caused when the parathyroid glands located in the neck make too much parathyroid hormone (PTH). This hormone controls the concentrations of calcium and phosphorus in your blood. Paricalcitol helps lower the amount of PTH which lowers the calcium and phosphorus concentrations.
This medicine is to be given only by or under the direct supervision of your doctor.
Before using Parsabiv
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of etelcalcetide injection in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of etelcalcetide injection in the elderly.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Other medical problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Bone disease or
- Heart failure or
- Seizures, or history of—Use with caution. May make these conditions worse.
- Heart rhythm problem (eg, congenital long QT syndrome, QT prolongation), or history of or
- Stomach or other digestive problems (eg, esophagitis, gastritis, ulcers)—May increase risk for more serious side effects.
Proper use of Parsabiv
A nurse or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins.
This medicine needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions.
Precautions while using Parsabiv
Your doctor will check your progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it. Blood and urine tests may be needed to check for unwanted effects.
Using this medicine may cause hypocalcemia (low calcium levels in the blood). Tell your doctor if you have numbness and tingling around the mouth, fingertips, or feet, muscle spasms, seizures, or fast or uneven heartbeat after receiving this medicine.
If you are rapidly gaining weight, having shortness of breath, chest pain, extreme tiredness or weakness, irregular breathing, irregular heartbeat, or excessive swelling of the hands, wrist, ankles, or feet, check with your doctor immediately. These may be symptoms of heart problems or your body keeping too much water.
This medicine may cause stomach bleeding. Tell your doctor right away if you have bloody or black, tarry stools, vomiting of blood or material that looks like coffee grounds, severe stomach pain, or constipation.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Parsabiv side effects
Check with your doctor or nurse immediately if any of the following side effects occur:
- Abdominal or stomach cramps
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- difficulty with breathing
- irregular heartbeats
- muscle cramps in the hands, arms, feet, legs, or face
- muscle spasms
- numbness and tingling around the mouth, fingertips, or feet
- Chest pain
- decreased urine output
- difficulty with swallowing
- dilated neck veins
- extreme fatigue
- irregular breathing
- reddening of the skin, especially around the ears
- swelling of the eyes, face, fingers, feet, lower legs, or inside of the nose
- tightness in the chest
- unusual tiredness or weakness
- weight gain
Incidence not known
- Bloody or black, tarry stools
- irregular heartbeat recurrent
- severe stomach pain
- vomiting of blood or material that looks like coffee grounds
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More about Parsabiv (etelcalcetide)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: calcimimetics
- FDA Approval History