Generic name: levofloxacin (lee-voe-FLOX-a-sin)
Drug class: Ophthalmic anti-infectives
Medically reviewed by Drugs.com. Last updated on May 2, 2021.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Antibiotic
Chemical Class: Fluoroquinolone
Uses for levofloxacin
Ophthalmic levofloxacin is used in the eye to treat bacterial infections of the eye. Ophthalmic levofloxacin works by killing bacteria.
Levofloxacin is available only with your doctor's prescription.
Before using levofloxacin
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For levofloxacin, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to levofloxacin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Use is not recommended in infants under 1 year of age. In children older than 1 year, levofloxacin is not expected to cause different side effects or problems than it does in adults.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of levofloxacin in the elderly with use in other age groups, levofloxacin is not expected to cause different side effects or problems in older people than it does in younger adults.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking levofloxacin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using levofloxacin with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using levofloxacin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Aripiprazole Lauroxil
- Arsenic Trioxide
- Cholera Vaccine, Live
- Inotuzumab Ozogamicin
- Insulin Aspart, Recombinant
- Insulin Bovine
- Insulin Degludec
- Insulin Detemir
- Insulin Glargine, Recombinant
- Insulin Glulisine
- Insulin Lispro, Recombinant
- Magnesium Sulfate
- Sodium Phosphate
- Sodium Phosphate, Dibasic
- Sodium Phosphate, Monobasic
Using levofloxacin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Aminolevulinic Acid
- Lanthanum Carbonate
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Proper use of levofloxacin
The dose of levofloxacin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of levofloxacin. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
To use levofloxacin ophthalmic solution (eye drops):
- First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
- If you think you did not get the drop of medicine into your eyes properly, use another drop.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.
- For ophthalmic solution dosage form:
- For bacterial conjunctivitis:
- Adults and children 1 year of age and older—Days 1 and 2: Put one to two drops in the affected eye(s) every two hours while awake. Do not put drops in more than 8 times a day. Days 3 through 7: Put one to two drops in the affected eye(s) every 4 hours while awake. Do not put drops in more than 4 times a day.
- Infants and children up to 1 year of age—Use and dose must be determined by your doctor.
- For bacterial conjunctivitis:
If you miss a dose of levofloxacin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Precautions while using levofloxacin
If your eye infection does not improve within a few days, or if it becomes worse, check with your doctor.
Levofloxacin may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort.
Levofloxacin side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- voice changes
- body aches or pain
- dryness or soreness of throat
- runny nose
- swelling of the eyelid
- tender, swollen glands in neck
- trouble in swallowing
- Itching, pain, redness or swelling of eye or eyelid
- watering of eyes
- decreased vision
- feeling of having something in the eye
- eye burning, dryness, itching, or pain
- increased sensitivity of eyes to light
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
More about levofloxacin ophthalmic
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Pricing & Coupons
- En Español
- 1 Review
- Drug class: ophthalmic anti-infectives