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Fluciclovine f 18 (Intravenous)

floo-SIK-loe-veen F 18

Medically reviewed on Oct 4, 2018

Commonly used brand name(s)

In the U.S.

  • Axumin

Available Dosage Forms:

  • Solution

Therapeutic Class: Diagnostic Agent, Radiopharmaceutical Imaging

Uses For fluciclovine f 18

Fluciclovine F 18 injection is used to help diagnose recurrent prostate cancer. It is used for a procedure called positron emission tomography (PET) scan to detect tumors.

Fluciclovine F 18 is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents, which may be used to find and treat certain diseases or to study the function of the body's organs.

Fluciclovine f 18 is to be given only by or under the direct supervision of a doctor with specialized training in nuclear medicine.

Before Using fluciclovine f 18

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to fluciclovine f 18 or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of fluciclovine F 18 injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fluciclovine F 18 injection in the elderly.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of fluciclovine f 18

A doctor or other trained health professional will give you fluciclovine f 18. Fluciclovine f 18 is given through a needle placed in one of your veins just before you have a PET scan.

Avoid significant exercises for at least 1 day before the PET scan.

Do not eat or drink anything for at least 4 hours before you receive fluciclovine f 18 (other than small amounts of water for taking other medicines).

You will need to urinate right away and as often as possible for at least 1 hour after the PET scan.

Precautions While Using fluciclovine f 18

It is very important that your doctor check you closely while you are receiving fluciclovine f 18. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.

Fluciclovine f 18 may cause serious allergic reactions, including anaphylaxis. Anaphylaxis requires immediate medical attention. The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, or fainting. Other signs may include changes in color of the skin of the face, very fast but irregular heartbeat or pulse, hive-like swellings on the skin, and puffiness or swellings of the eyelids or around the eyes. If these side effects occur, tell your doctor right away.

While receiving fluciclovine f 18, you will be exposed to radiation. If you have any questions about this, talk to your doctor.

Fluciclovine f 18 Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

  • Cough
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives, itching, or skin rash
  • puffiness or swelling of the eyelids or around the eyes, face, lips, throat, or tongue
  • tightness in the chest
  • trouble breathing
  • unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

  • Change in taste
  • loss of taste
  • redness or pain at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More about fluciclovine F 18

Consumer resources

Other brands: Axumin

Professional resources

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