Skip to Content

Medications for Sinus Symptoms

About Sinus Symptoms:  Sinus symptoms are associated with a variety of upper respiratory tract disorders including the common cold, sinus infection, hay fever and are characterized by congestion of the nasal mucous membrane, watery nasal rhinorrhea, facial pain especially around eyes, nose & forehead, earache, dental pain, sneezing, fever and bad breath.

Drugs Used to Treat Sinus Symptoms

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Activity
Norel AD N N X 1 review 2.0

Generic name: acetaminophen / chlorpheniramine / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Propel C N Add review 0.0

Generic name: mometasone nasal

For consumers: dosage, interactions, side effects

Sudafed 12 Hour Pressure+Pain N N X Add review 0.0

Generic name: naproxen / pseudoephedrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Tylenol Allergy Multi-Symptom N N X Add review 0.0

Generic name: acetaminophen / chlorpheniramine / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

acetaminophen / pseudoephedrine N N X 8 reviews 10

Generic name: acetaminophen / pseudoephedrine systemic

Brand names:  Allerest No Drowsiness, Ornex, Dristan Cold Non-Drowsy, Nexafed Sinus Pressure + Pain …show all

Drug class: upper respiratory combinations

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

Advil Cold and Sinus Liqui-Gels C N X 2 reviews 10

Generic name: ibuprofen / pseudoephedrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Vicks Dayquil Cold & Flu Relief N N X 1 review 10

Generic name: acetaminophen / dextromethorphan / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

acetaminophen / phenylephrine N N X 4 reviews 8.3

Generic name: acetaminophen / phenylephrine systemic

Brand names:  Sudafed PE Sinus Pressure + Pain, Tylenol Sinus + Headache Day, Vicks Sinex Daytime, Excedrin Sinus Headache, Robitussin Peak Cold Nasal Relief, Contac Cold + Flu (Day Formula), Mapap Sinus Congestion and Pain, Sinus Congestion and Pain Daytime Cool Ice, Vicks QlearQuil Daytime Sinus & Congestion …show all

Drug class: upper respiratory combinations

For consumers: dosage, interactions,

Allergy Multi-Symptom N N X Add review 0.0

Generic name: acetaminophen / chlorpheniramine / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Tylenol Sinus + Headache Day N N X Add review 0.0

Generic name: acetaminophen / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

acetaminophen / chlorpheniramine / phenylephrine N N X 3 reviews 7.3

Generic name: acetaminophen / chlorpheniramine / phenylephrine systemic

Brand names:  Allergy Multi-Symptom, Norel AD, Tylenol Allergy Multi-Symptom, Tylenol Sinus Congestion & Pain Nighttime, Dristan Cold Multi Symptom Formula, Comtrex Severe Cold & Sinus, Robitussin Peak Cold Nighttime Nasal Relief, Comtrex Flu Therapy, Contac Cold + Flu (Night Formula), GNP Cold Relief Plus, Medicidin-D, Onset Forte, Super Strength Sinadrin, Tylenol Plus Children's Cold …show all

Drug class: upper respiratory combinations

For consumers: dosage, interactions,

Aleve-D Sinus & Cold N N X 2 reviews 9.5

Generic name: naproxen / pseudoephedrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

guaifenesin / phenylephrine C N 6 reviews 10

Generic name: guaifenesin / phenylephrine systemic

Brand names:  Deconex, Gilphex TR, Deconex IR, Aldex G, Aquatab D, Crantex, D-Phen 1000, Donatussin Drops, Duravent PE, Guiatex PE, Nariz, Prolex D, Rescon-GG, Supress-PE, Triaminic Chest & Nasal Congestion, Xpect-PE, Zotex-GP …show all

Drug class: upper respiratory combinations

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, Prescribing Information

ibuprofen / pseudoephedrine C N X 35 reviews 7.7

Generic name: ibuprofen / pseudoephedrine systemic

Brand names:  Advil Cold and Sinus, Advil Cold and Sinus Liqui-Gels, Advil Children's Cold, Motrin Childrens Cold …show all

Drug class: upper respiratory combinations

For consumers: dosage, interactions,

For professionals: Prescribing Information

Sudafed PE Sinus Pressure + Pain N N X 1 review 4.0

Generic name: acetaminophen / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

mometasone C N 21 reviews 2.8

Generic name: mometasone nasal

Brand names:  Nasonex, Propel

Drug class: nasal steroids

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Nasonex C N 13 reviews 3.6

Generic name: mometasone nasal

Drug class: nasal steroids

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Advil Cold and Sinus C N X 30 reviews 7.5

Generic name: ibuprofen / pseudoephedrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Alternative treatments for Sinus Symptoms

The following products are considered to be alternative treatments or natural remedies for Sinus Symptoms. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Sinus Symptoms.

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Browse Treatment Options

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.