Sodium oxybate Alternatives Compared
| Sodium oxybate | Sunosi (solriamfetol) | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) |
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| Sodium oxybate | Sunosi (solriamfetol) | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) |
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Prescription only
Prescribed for Idiopathic Hypersomnia, Cataplexy, Narcolepsy, Fibromyalgia. Sodium oxybate may also be used for purposes not listed in this medication guide. |
Prescription only
Sunosi is a once-daily medication that may be used to increase wakefulness in people with narcolepsy or obstructive sleep apnea (OSA). It can increase blood pressure and common side effects include... View more |
Prescription only
Xywav may be used to treat idiopathic hypersomnia in adults or narcolepsy in adults and children aged 7 and older. It contains 92% less sodium than sodium oxybate (Xyrem) because it is made up of a... View more |
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| More about Sodium oxybate | More about Sunosi (solriamfetol) | More about Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Sodium oxybate has an average rating of 7.8 out of 10 from a total of 127 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 13% reported a negative effect. |
Sunosi has an average rating of 5.4 out of 10 from a total of 81 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 36% reported a negative effect. |
Xywav has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 13% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Sodium oxybate side effects |
View all Sunosi side effects |
View all Xywav side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Sodium oxybate prices |
View all Sunosi prices |
View all Xywav prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Lumryz, Xyrem |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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1 hour |
7.1 hours |
0.66 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 346 drugs are known to interact with Sodium oxybate:
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A total of 81 drugs are known to interact with Sunosi:
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A total of 346 drugs are known to interact with Xywav:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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May 01, 2023 |
March 20, 2019 |
July 21, 2020 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Xyrem
Xyrem (sodium oxybate) is an oral prescription solution that may be used to treat cataplexy or ...
Xywav
Xywav is used for the treatment of cataplexy and excessive daytime sleepiness (EDS) in patients ...
Sunosi
Sunosi (solriamfetol) is a prescription medicine used for the treatment of excessive sleepiness in ...
Adderall
Adderall (amphetamine and dextroamphetamine) is used to treat narcolepsy and ADHD. Includes side ...
Concerta
Concerta is used to treat attention deficit disorder (ADD) and attention deficit hyperactivity ...
Ritalin
Ritalin (methylphenidate) is used to treat attention deficit disorder (ADD) and narcolepsy ...
Provigil
Provigil promotes wakefulness and is used to treat excessive daytime sleepiness caused by ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.