Rapamune Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Rapamune	CellCept	Tacrolimus	Enter another drug to compare

Rapamune (sirolimus)

CellCept (mycophenolate mofetil)

Tacrolimus

Prescription only

Prescribed for Lymphangioleiomyomatosis, Organ Transplant - Rejection Prophylaxis. Rapamune may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Nephrotic Syndrome, Organ Transplant - Rejection Prophylaxis. CellCept may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Organ Transplant - Rejection Prophylaxis, Organ Transplant - Rejection Reversal. May also be prescribed off label for Nephrotic Syndrome, Graft-versus-host disease, Crohn's Disease.

More about Rapamune (sirolimus)

More about CellCept (mycophenolate mofetil)

More about Tacrolimus

Generic Status

Lower-cost generic is available

Ratings & Reviews

Rapamune has an average rating of 0.0 out of 10 from a total of 1 ratings on Drugs.com.

CellCept has an average rating of 8.5 out of 10 from a total of 12 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 3% reported a negative effect.

Tacrolimus has an average rating of 8.0 out of 10 from a total of 46 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 10% reported a negative effect.

View all 1 reviews

View all 12 reviews

View all 46 reviews

Drug Class

Selective immunosuppressants

Calcineurin inhibitors

Side Effects

Common side effects include:

upper respiratory tract infection
urinary tract infection

See also: Rapamune side effects in more detail.

Common side effects include:

asthma
herpes simplex infection
infection
metabolic acidosis
oral candidiasis
pleural effusion
respiratory tract infection
systemic cytomegalovirus disease
urinary tract infection
viremia
abdominal pain
acne vulgaris
anemia
anxiety
asthenia
back pain
cardiovascular disorder
chest pain
constipation
cough
depression
diarrhea
disorder of integument
drowsiness
dyspepsia
dyspnea
edema
fever
headache
hypercholesterolemia
hyperlipidemia
hypertension
hypertonia
hyperuricemia
hypervolemia
hypokalemia
hypotension
increased lactate dehydrogenase
increased serum alanine aminotransferase
increased serum aspartate aminotransferase
increased serum creatinine
leukopenia
lower limb cramp
myalgia
myasthenia
nausea
pain
paresthesia
peripheral edema
pulmonary disease
rhinitis
sinusitis
tachycardia
thrombocytopenia
tremor
vomiting
weight gain
chills
flatulence
show all 59

See also: CellCept side effects in more detail.

Commonly reported side effects include:

opportunistic infection
diabetes mellitus
infection
headache
hyperglycemia
hyperkalemia
increased blood urea nitrogen
increased serum creatinine
mental status changes
nephrotoxicity
sensation disorder
tremor
show all 12

See also: tacrolimus side effects in more detail.

Pricing and Coupons * Prices are without insurance

Quantity	100 tablet
Dosage	0.5 mg
Per Unit^*	$17.50
Cost^*	$1,749.76

View all Rapamune prices and generic prices

Quantity	100 capsule
Dosage	250 mg
Per Unit^*	$9.57
Cost^*	$956.77

View all CellCept prices and generic prices

Quantity	100 each
Dosage	1 mg
Per Unit^*	$1.49 - $1.88
Cost^*	$148.93 - $187.70

View all tacrolimus prices

Get free Discount Card

Dosage Form(s) Available

Oral solution
Oral tablet

Intravenous powder for injection
Oral capsule
Oral powder for reconstitution
Oral tablet

Oral capsule

Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

78 hours

18 hours

21.2 hours

CSA Schedule ** View glossary of terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 626 drugs are known to interact with Rapamune:

167 major drug interactions (638 brand and generic names)
451 moderate drug interactions (1662 brand and generic names)
8 minor drug interactions (35 brand and generic names)

A total of 302 drugs are known to interact with CellCept:

47 major drug interactions (207 brand and generic names)
226 moderate drug interactions (804 brand and generic names)
29 minor drug interactions (1367 brand and generic names)

A total of 780 drugs are known to interact with tacrolimus:

237 major drug interactions (874 brand and generic names)
526 moderate drug interactions (1931 brand and generic names)
17 minor drug interactions (131 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Grapefruit and grapefruit juice may interact with sirolimus and could lead to potentially dangerous... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Tacrolimus should be taken on a consistent schedule before or after you eat at the same times each... View more

Disease Interactions

First Approval Date

September 15, 1999

May 03, 1995

April 08, 1994

WADA Class View World Anti-Doping Agency classifications.

N/A

More Information

Patient resources

Overview

Professional Resources

Prescribing information

Prescribing information

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Rapamune Alternatives Compared

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