Opvee Alternatives Compared
| Opvee | Naloxone | Narcan |
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| Opvee (nalmefene) | Naloxone | Narcan (naloxone) |
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Prescription only
Prescribed for Opioid Overdose. Opvee may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Naloxone can be used by consumers and the lay-public, first-responders and healthcare providers to help reverse an overdose due to opioids (narcotics), including heroin and prescription opioids. It... View more |
Over-the-counter
Prescribed for Opioid Overdose. Narcan may also be used for purposes not listed in this medication guide. |
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| More about Opvee (nalmefene) | More about Naloxone | More about Narcan (naloxone) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Be the first to share your experience with this drug. |
Naloxone has an average rating of 7.9 out of 10 from a total of 26 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 21% reported a negative effect. |
Narcan has an average rating of 8.2 out of 10 from a total of 5 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: Opvee side effects in more detail. |
See also: naloxone side effects in more detail. |
See also: Narcan side effects in more detail. |
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| Generic Availability | ||||||||||||||||||||||||||
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N/A |
Lower cost generic |
Lower cost generic approved | ||||||||||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Opvee prices |
View all naloxone prices |
View all Narcan prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other nalmefene brands include: Zurnai | Kloxxado, Narcan, Rextovy, Rezenopy, RiVive, Zimhi | Other naloxone brands include: Kloxxado, Rextovy, Rezenopy, RiVive, Zimhi | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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8.6 hours |
3 hours |
3 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 6 drugs are known to interact with Opvee:
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A total of 30 drugs are known to interact with naloxone:
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A total of 30 drugs are known to interact with Narcan:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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N/A |
April 13, 1971 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.