Comparing Isotretinoin vs Mekinist
Isotretinoin | Mekinist |
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Isotretinoin | Mekinist (trametinib) |
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Prescription only
Prescribed for Rosacea, Acne, Acute Nonlymphocytic Leukemia, Granuloma Annulare, Pityriasis rubra pilaris, Melanoma - Metastatic. isotretinoin may also be used for purposes not listed in this medication guide. View more |
Prescription only
Prescribed for Melanoma - Metastatic, Low-Grade Glioma, Thyroid Cancer, Non Small Cell Lung Cancer, Solid Tumors. Mekinist may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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More about Isotretinoin | More about Mekinist (trametinib) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Isotretinoin has an average rating of 8.0 out of 10 from a total of 1056 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 13% reported a negative effect. |
Mekinist has an average rating of 7.3 out of 10 from a total of 3 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 33% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: isotretinoin side effects in more detail. |
See also: Mekinist side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all isotretinoin prices |
View all Mekinist prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Absorica, Absorica LD, Accutane, Amnesteem, Claravis, Myorisan, Sotret, Zenatane |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
32 hours |
115.2 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 133 drugs are known to interact with isotretinoin:
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A total of 20 drugs are known to interact with Mekinist:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
May 07, 1982 |
May 29, 2013 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.