Icatibant Alternatives Compared
| Icatibant | Haegarda (C1 esterase inhibitor (human)) | Orladeyo (berotralstat) |
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| Icatibant | Haegarda (C1 esterase inhibitor (human)) | Orladeyo (berotralstat) |
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Prescription only
Prescribed for Hereditary Angioedema. Icatibant may also be used for purposes not listed in this medication guide. |
Prescription only
Haegarda works by replacing missing C1 protein in the blood of adults and children over the age of 6 with hereditary angioedema (HAE) preventing the generation of bradykinin and angioedema attacks... View more |
Prescription only
Orladeyo is an oral, once-daily medication that is taken to reduce angioedema attacks in adults and children over the age of 12 with HAE. It is the only oral preventive currently available (the... View more |
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| More about Icatibant | More about Haegarda (C1 esterase inhibitor (human)) | More about Orladeyo (berotralstat) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Icatibant has an average rating of 8.4 out of 10 from a total of 10 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 20% reported a negative effect. |
Haegarda has an average rating of 8.0 out of 10 from a total of 2 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Orladeyo has an average rating of 6.7 out of 10 from a total of 3 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Icatibant side effects |
View all Haegarda side effects |
View all Orladeyo side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Icatibant prices |
View all Haegarda prices |
View all Orladeyo prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Firazyr | Other C1 esterase inhibitor (human) brands include: Berinert, Cinryze |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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1.8 hours |
152 hours |
152 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 11 drugs are known to interact with Icatibant:
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A total of 51 drugs are known to interact with Haegarda:
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A total of 523 drugs are known to interact with Orladeyo:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||||||||||
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August 25, 2011 |
N/A |
December 03, 2020 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Ruconest
Ruconest is used to treat angioedema attacks in adult and adolescent patients with Hereditary ...
Firazyr
Firazyr is used for hereditary angioedema (HAE) to treat acute HAE attacks in adults 18 years and ...
Cinryze
Cinryze (complement C1 esterase inhibitor) is used to prevent attacks of angioedema in people with ...
Orladeyo
Orladeyo (berotralstat) is used to prevent attacks of hereditary angioedema (HAE). Includes ...
Haegarda
Haegarda is an injectable protein replacement therapy that prevents swelling and attacks in ...
Takhzyro
Takhzyro (lanadelumab-flyo) is used to prevent hereditary angioedema (HAE) and reduce symptoms ...
Berinert
Berinert is used to treat acute abdominal, facial, or laryngeal hereditary angioedema (HAE) attacks ...
Andembry
Andembry is used to prevent attacks of Hereditary Angioedema (HAE) in adults and children 12 years ...
Kalbitor
Kalbitor injection is used to treat acute attacks of hereditary angioedema (HAE) in patients 12 ...
Stanozolol
Stanozolol is used in the treatment of hereditary angioedema, which causes episodes of swelling of ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.