Comparing Estrace vs Vagifem
Estrace | Vagifem |
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Estrace (estradiol) | Vagifem (estradiol) |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Postmenopausal Symptoms, Hypoestrogenism, Oophorectomy, Breast Cancer - Palliative, Primary Ovarian Failure, Prostate Cancer. Estrace may also... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis. Vagifem may also be used for purposes not listed in this medication guide. |
Related suggestions Atrophic Vaginitis
Atrophic Urethritis
Popular comparisons
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More about Estrace (estradiol) | More about Vagifem (estradiol) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Estrace has an average rating of 7.4 out of 10 from a total of 12 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
Vagifem has an average rating of 6.2 out of 10 from a total of 100 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 33% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Estrace side effects in more detail. |
See also: Vagifem side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic approved | |||||||||||||||||
Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Estrace prices |
View all Vagifem prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other estradiol brands include: Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Other estradiol brands include: Estrace Vaginal Cream, Estring, Imvexxy, Yuvafem | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
16 hours |
N/A |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 363 drugs are known to interact with Estrace:
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A total of 231 drugs are known to interact with Vagifem:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
July 23, 1975 |
March 26, 1999 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
N/A |
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Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.