Comparing Donepezil vs Melatonin
| Donepezil | Melatonin |
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| Donepezil | Melatonin |
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Prescription only
Donepezil boosts the effects of acetylcholine, a neurotransmitter that is noticeably depleted in people with Alzheimer's disease. Side effects are more likely at higher dosages and include nausea... View more |
Prescription and OTC
Supplemental melatonin is very effective at reducing symptoms of jet lag, particularly that brought about by eastward travel across five or more time zones. Melatonin may also be used to treat sleep... View more |
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| More about Donepezil | More about Melatonin | ||||||||
| Ratings & Reviews | |||||||||
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Donepezil has an average rating of 5.8 out of 10 from a total of 141 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 32% reported a negative effect. |
Melatonin has an average rating of 5.7 out of 10 from a total of 239 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 37% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Donepezil side effects |
View all Melatonin side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Donepezil prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Adlarity, Aricept, Aricept ODT | Bio-Melatonin, Melatonin Time Release, SGard, Sleep3 | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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70 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category N
Not classified
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| Drug Interactions | |||||||||
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A total of 527 drugs are known to interact with Donepezil:
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A total of 342 drugs are known to interact with Melatonin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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November 25, 1996 |
N/A |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.