Comparing Depakote vs Dilantin
Depakote | Dilantin |
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Depakote (divalproex sodium) | Dilantin (phenytoin) |
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Prescription only
Depakote may be used in the treatment of epilepsy and mania, and to prevent migraines; however, people taking Depakote should be monitored for potentially fatal side effects such as liver failure... View more |
Prescription only
Prescribed for Seizures, Epilepsy, Neurosurgery, Status Epilepticus, Seizure Prophylaxis During or Following Neurosurgery. Dilantin may also be used for purposes not listed in this medication guide. |
Related suggestions |
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More about Depakote (divalproex sodium) | More about Dilantin (phenytoin) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Depakote has an average rating of 6.3 out of 10 from a total of 324 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 28% reported a negative effect. |
Dilantin has an average rating of 7.6 out of 10 from a total of 77 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 18% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Depakote side effects in more detail. |
See also: Dilantin side effects in more detail. |
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Generic Availability | |||||||||||||||||
Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Depakote prices |
View all Dilantin prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other divalproex sodium brands include: Depakote ER, Depakote Sprinkles | Other phenytoin brands include: Di-Phen, Phenytek, Phenytoin Sodium, Phenytoin Sodium, Extended Release | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
16 hours |
15 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 404 drugs are known to interact with Depakote:
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A total of 833 drugs are known to interact with Dilantin:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
March 10, 1983 |
January 06, 1953 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.