C1 esterase inhibitor (human) Alternatives Compared
C1 esterase inhibitor (human) | Berinert | Orladeyo |
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C1 esterase inhibitor (human) | Berinert (C1 esterase inhibitor (human)) | Orladeyo (berotralstat) |
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Prescription only
Prescribed for Hereditary Angioedema. C1 esterase inhibitor (human) may also be used for purposes not listed in this medication guide. |
Prescription only
Berinert is used to treat hereditary angioedema (HAE) in adults and children and people can be taught how to self-administer it intravenously at home. An increase in the severity of pain associated... View more |
Prescription only
Orladeyo is an oral, once-daily medication that is taken to reduce angioedema attacks in adults and children over the age of 12 with HAE. It is the only oral preventive currently available (the... View more |
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More about C1 esterase inhibitor (human) | More about Berinert (C1 esterase inhibitor (human)) | More about Orladeyo (berotralstat) | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
C1 esterase inhibitor (human) has an average rating of 8.5 out of 10 from a total of 6 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 17% reported a negative effect. |
Berinert has an average rating of 10.0 out of 10 from a total of 2 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Orladeyo has an average rating of 6.7 out of 10 from a total of 3 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 0% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: C1 esterase inhibitor (human) side effects in more detail. |
See also: Berinert side effects in more detail. |
See also: Orladeyo side effects in more detail. |
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Generic Availability | ||||||||||||||||||
N/A |
N/A |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Berinert prices |
View all Orladeyo prices |
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Dosage Forms Available | ||||||||||||||||||
N/A |
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Brand Names | ||||||||||||||||||
Berinert, Cinryze, Haegarda | Other C1 esterase inhibitor (human) brands include: Cinryze, Haegarda |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
152 hours |
152 hours |
152 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 49 drugs are known to interact with C1 esterase inhibitor (human):
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A total of 49 drugs are known to interact with Berinert:
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A total of 456 drugs are known to interact with Orladeyo:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||
First Approval Date | ||||||||||||||||||
N/A |
N/A |
December 03, 2020 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.