Comparing Aldactone vs Differin
Aldactone | Differin |
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Aldactone (spironolactone) | Differin (adapalene) |
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Prescription only
Prescribed for Acne, Alopecia, Edema, Heart Failure, High Blood Pressure, Hirsutism, Hypokalemia, Primary Hyperaldosteronism, Primary Hyperaldosteronism Diagnosis. Aldactone may also be used for... View more |
Prescription and OTC
Prescribed for Acne. Differin may also be used for purposes not listed in this medication guide. |
Related suggestions |
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More about Aldactone (spironolactone) | More about Differin (adapalene) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Aldactone has an average rating of 6.5 out of 10 from a total of 27 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 36% reported a negative effect. |
Differin has an average rating of 6.0 out of 10 from a total of 340 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 37% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Aldactone side effects in more detail. |
See also: Differin side effects in more detail. |
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Generic Availability | |||||||||||||||||
Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Aldactone prices |
View all Differin prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other spironolactone brands include: CaroSpir | Other adapalene brands include: Plixda | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
37 hours |
51 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 382 drugs are known to interact with Aldactone:
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A total of 12 drugs are known to interact with Differin:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
January 21, 1960 |
May 31, 1996 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.