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Saliva substitutes topical for Xerostomia User Reviews

Brand names: Biotene Mouthwash, Mouth Kote, XyliMelts, Glandosane Unflavored, Dry Mouth Mouthwash, Biotene Moisturizing Mouth Spray, Moi-Stir, SalivaMAX, Optimoist, Aquoral, Biotene Dry Mouth Toothpaste, Biotene PBF Dry Mouth Toothpaste, Biotene Oral Balance, Orajel Dry Mouth Moisturizing, Aquae, Stoppers 4 Dry Mouth, Caphosol, NeutraSal, Glandosane Peppermint, Glandosane Lemon, AS Saliva Orthana Bioxtra Numoisyn Oasis Moisturizing Mouth …show all brand names

Saliva substitutes topical has an average rating of 5.6 out of 10 from a total of 43 reviews for the treatment of Xerostomia. 40% of reviewers reported a positive experience, while 42% reported a negative experience.

Saliva substitutes topical rating summary

5.6/10 average rating

43 ratings from 48 user reviews.

Compare all 23 medications used in the treatment of Xerostomia.

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Reviews for Saliva substitutes topical

  • Ann
  • April 21, 2022

XyliMelts (saliva substitutes) "I had a very bad experience after taking Xylimelts. At first I did not know what was causing me to feel so unwell. My tongue was extra swollen and felt hot. I had Tingling in my mouth and tongue. My voice was very hoarse and a tightness in my chest. I started to shake slightly throughout my arms. legs and body. I did not know what was causing it and I rang a health line. I wondered if I had Covid though I rarely go out. As there was no warning on the box of medication I did not connect to start with then as I had not taken anything else I decided to google to see if that showed any side effects. It certainly did. I went to my doctor's and I was given another medication which did help. However it was a holiday so the night it happened I had nowhere to call apart from going to emergency dept. I am telling you this because I think you should state all the possible side effects on your medication on the enclosed leaflet or box. boxes. That way an earlier diagnosis can be made. I"

1 / 10
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31 Report
  • Phomp
  • Taken for less than 1 month
  • October 23, 2018

XyliMelts (saliva substitutes) "I started using Xyligel (my dentist gave me a sample) it works wonderfully. After using it for 4 days my gums and teeth hurt.. Last night I had to get up and brush my teeth and use a mouth wash because my gums hurt so much, I was getting scared. If I bite down on anything my teeth hurt. I am so disappointed that I can't use XyliGel anymore, it worked so well for me. Something is very wrong. I've been reading reviews on this product and a great many people are experiencing the same thing."

2 / 10
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62 Report
  • grand...
  • Taken for 1 to 6 months
  • December 1, 2019

XyliMelts (saliva substitutes) "I have dry mouth due to Sicca syndrome and at first I thought it was wonderful in relieving dry mouth at night. Gradually over several months, I had gastric issues and sensitive teeth. Also had to have 2 root canals in previously good teeth (related?). When it got really uncomfortable, I visited my doctor due to black gassy stools several times a day, terrible gas, pressure and rumbling in the stomach. Then re-flux started. Stool test and blood test were normal so Dr. made appt. with gastroenterologist (not seen yet). I found a reference to gastric side affect from Xylitol. I stopped using the xylimelts and symptoms went away."

2 / 10
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44 Report
  • Kissi...
  • Taken for 6 months to 1 year
  • August 7, 2013

Mouth Kote (saliva substitutes) "I take Vesicare for an overactive bladder. It helps a lot, but the side effect is extreme dry mouth!! I tried Bioteen and didn't like the taste. I then tried TheraBreath lozengers which seemed to help, but I didn't like waking up in the night and needing to suck on a strong mint flavored lozenger. When I tried Mouthkote spray I had instant relief and it left no real bad taste in my mouth. The bottle is next to me at night, so when I wake up with a Sahara desert in my mouth, I simply spray a couple times into my mouth, swish it around for 10 seconds, and fall right back to sleep."

10 / 10
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70 Report
  • Della
  • Taken for less than 1 month
  • April 28, 2023

XyliMelts (saliva substitutes) "After being put on a CPAP machine, I purchased XyliMelts Dry Mouth Stick on Melts. The night I used them, I did experience significant relief from dry mouth. However, I ended up with two severe sores on each side of my mouth in the area where I used the product. It has been a week since I used them, and the sores are still painful and present. I have not used XyliMelts since then. What I find concerning is that although other people have reported this side effect, I cannot find any information from the manufacturer stating that it can cause mouth ulcers or sores as a side effect. The only mention I found was that a small number of people can be allergic to the adhesive and should buy the product with a different form of adhesive."

2 / 10
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12 Report

Are you taking this medicine?

  • Allie
  • July 12, 2021

XyliMelts (saliva substitutes) "I’ve been using Xilomelts for several months and they were great at first . It seems I have developed an allergy to them . My mouth became so irritated that it was hard to eat anything. Corners of my mouth were a mess too. I didn’t realize that it was the xilimelts Thats was causing it until I stopped using them to experiment and see. Sure enough, the irritation stopped slowly . I won’t use them again . I’m so sad because they let me get a little sleep at night ."

1 / 10
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25 Report
  • Relei...
  • Taken for 1 to 6 months
  • January 21, 2013

Mouth Kote (saliva substitutes) "Have dry and painful mouth of unknown cause. I have tried Biotene mouth wash, the rubbery losenges and several other treatments, but finally found Mouth Kote. Clearly the best for me. Lime (but not sweet) tasting. Causes you to make saliva when spraying in. I seem to be able to use it as often as I like. Really helps."

10 / 10
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59 Report
  • Ann
  • Taken for 1 to 2 years
  • December 7, 2020

XyliMelts (saliva substitutes) "XyliMelts was recommended by my dentist’s office for dry mouth caused by meds that I am on. Used nightly as instructed for 1 year. Decayed front tooth in my bridge & 3 teeth in my lower jaw. Having to get dental implants & already got 3 crowns in lower jaw. Cost approximately $7k. Wish I never heard of Xylimelts."

1 / 10
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22 Report
  • spark...
  • June 18, 2018

XyliMelts (saliva substitutes) "I have sjogren's and loved xylimelts as it meant I could sleep several hours without a drink. But had a side effect of diarrhea and didn't associate it with xylimelts for 4 months even after other meds changes and gastro tests. Eliminated them 3 weeks ago and no diarrhea so xylitol was the culprit. Now thinking of trying mouth kote."

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32 Report
  • Alyss...
  • August 7, 2016

Biotene Moisturizing Mouth Spray (saliva substitutes) "Biotene went down my throat and fused my epiglottis shut so that I could not breathe. Finally freed it and developed pneumonia and spent three days in hospital. I was told it had wax in it. Very dangerous. Deadly"

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39 Report
  • Ngp
  • Taken for less than 1 month
  • August 27, 2022

XyliMelts (saliva substitutes) "I have diabetes and started using these for dry mouth. My blood sugar hasn't been over 180 for a year. Within a few days of using these my blood sugar was reading in the 250’s and higher with no other changes in my life except for the xylitol. It doesn't make sense because there is no sugar in the product and xylitol is not supposed to raise blood sugar but there it is!"

5 / 10
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10 Report
  • JLano
  • Taken for 2 to 5 years
  • January 21, 2020

XyliMelts (saliva substitutes) "Have used xyliMelts for years for dry mouth at night. Definitely helps with sleep. Sometimes the area of the gum where I put the xyliMelts is a little sensitive, but worth it for the sleep. Have tried other products, but these are the best. I am 80 and developed this dry mouth at night about five years ago. No real cause determined. Discovered this product by trial and error. Dentists need to be informed. I told my dentist and she now recommends this product."

10 / 10
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20 Report
  • CPM
  • Taken for 1 to 6 months
  • January 28, 2020

XyliMelts (saliva substitutes) "Been taking Xylimelts at night ( 1) for dry mouth due to breathing thru my mouth while sleeping. I'm 66 and I have OSA. During dry winter months while sleeping I would wake up with a terribly parched mouth several times a night. This really helps !! Side effect - seems to act like a mild laxative...."

8 / 10
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18 Report
  • TDawg
  • Taken for 1 to 6 months
  • September 28, 2019

XyliMelts (saliva substitutes) "I've been using Xyimelts Tablets for about one month since I starting using the CPAP for sleep apnea to help dry mouth caused by the CPAP. So far I have had only positive results. I wake up in the AM after a nights rest and the tablet has dissolved. I may have to move my tongue around to completely spread the tablet but the overall effect is positive."

7 / 10
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18 Report
  • janco...
  • Taken for 6 months to 1 year
  • March 16, 2023

XyliMelts (saliva substitutes) "This caused major irritation on my tongue and in my mouth, similar to burnt tongue syndrome (yes, this is real condition). I discontinued the product and found my tongue and mouth improved immediately, with the condition going away completely in a few days. I will never take this again. Other products work without terrible side effects."

1 / 10
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6 Report
  • Warning
  • Taken for less than 1 month
  • May 28, 2022

XyliMelts (saliva substitutes) "I thought they were great at first but my tongue would be extra sensitive after using them. I stopped after a week or so but my dry mouth kept me up all night recently so last night I used another one. Today my tongue has little sores all over it and it hurts to eat. I won't be using these again."

1 / 10
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9 Report
  • PatM
  • January 15, 2017

Biotene Mouthwash (saliva substitutes) "I have sjogrens so have a dry mouth. From the first time I tried it I was impressed with no dryness from alcohol in my mouth, no burning. This mouth wash has kept my breathe and mouth slightly moist for awhile afterward use too. I highly recommend this for dry mouth, from medications or medical conditions."

10 / 10
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22 Report
  • MDD
  • Taken for 6 months to 1 year
  • September 21, 2016

NeutraSal (saliva substitutes) "I actually liked this product when I was using it, but hated the inconvenience of having to mix the powder. It was hard to use away from home. My doctor gave me a lot of samples but now he said it isn't available? Not sure why. I like a new product he gave me a sample of called Lubricity (it's an oral spray) and I love the convenience of it. It also seems to last considerably longer than NeutraSal and most of the other products I've tried. Unfortunately it's not in any stores by me yet"

6 / 10
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20 Report
  • Jess
  • Taken for less than 1 month
  • October 25, 2022

XyliMelts (saliva substitutes) "My dentist recommended these to me and I tried it last night, I have trouble with not being able to swallow my saliva at night. I went to bed fine but an hour later my throat started to close, my throat tighted like sand paper, I have bumps in my mouth, my whole neck and face hurt, it took away my good saliva and gave me this thick foam saliva that was hard to swallow. I took a claritin to at least help but I feel like I have a bad cold now."

1 / 10
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6 Report
  • Sally
  • Taken for 2 to 5 years
  • March 3, 2020

Biotene Oral Balance (saliva substitutes) "Husband has been using biotene spray for years due to the medicines that give him dry mouth. A few nights ago he sprayed some in his mouth and within a few minutes his throat constricted, he kept coughing and choking and I almost had to take him to the hospital. He drank some water and then took 2 antihistamines which seemed to help. He complained of a cough and soreness in throat for a couple of days after. He is better now."

7 / 10
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11 Report
  • Morgan...
  • Taken for 1 to 6 months
  • December 21, 2016

"I recently came across a new product that's on the market called Lubricity and I LOVE IT. It's an oral spray & so far seems to last MUCH longer than any other dry mouth spray I have ever used. I suffer from dry mouth & have for about 5 years. I ordered this product online since it's not sold in any stores near me. I came across it when doing some research online. They did offer a coupon code on the website when I bought it, seems like they have a different % off discount now but always seem to offer something. I HIGHLY RECOMMEND THIS!"

10 / 10
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15 Report
  • MikStgh
  • Taken for 2 to 5 years
  • January 3, 2023

XyliMelts (saliva substitutes) "I’ve been using it for about three years, for a dry mouth at night, ever since getting a CPAP machine. Usually use one a night and I put the tablet in a different location of my mouth each night. Have had great success with them and no side effects. I’d recommend that people try them to see if it works as well for them."

10 / 10
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3 Report
  • Becks
  • Taken for less than 1 month
  • August 14, 2021

XyliMelts (saliva substitutes) "I got a Cpap machine and my mouth has been cotton dry at night. Miserable. After around 6 months I got the first cavity I’ve had since I was 12 years old (I’m over 50). Since dry mouth causes cavities, I decided to try Xylimelts and WOW! I figured they would probably help some, hoping at least to make my mouth more comfortable at night, but I didn’t realize they could stimulate such saliva flow. I even drooled on my pillow. All I need is one a night. It sticks just right and is gone when I wake up. This is a fantastic product."

10 / 10
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5 Report
  • Jaack
  • Taken for 5 to 10 years
  • September 1, 2017

Salivart (saliva substitutes) "Probably the closest to real saliva. No nasty after taste, very liquid, pressurized spray can. ONLY negative is availability. Not many stores/pharmacies carry this. Trying company web site and ebay & Amazon"

10 / 10
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8 Report
  • Anonymous
  • Taken for less than 1 month
  • February 4, 2023

XyliMelts (saliva substitutes) "I just started using Xylimelts and have had success with them. However, I have experienced some digestive issues and have been waking up with a headache. I'm going to them for a short period and see if my symptoms recede."

3 / 10
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2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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