Saliva substitutes topical User Reviews & Ratings

• Ann...
• April 21, 2022

For Xerostomia "I had a very bad experience after taking XyliMelts. At first, I did not know what was causing me to feel so unwell. My tongue was extra swollen and felt hot. I had tingling in my mouth and tongue. My voice was very hoarse and a tightness in my chest. I started to shake slightly throughout my arms, legs, and body. I did not know what was causing it, and I rang a health line. I wondered if I had COVID, though I rarely go out. As there was no warning on the box of medication, I did not connect to start with. Then, as I had not taken anything else, I decided to Google to see if that showed any side effects. It certainly did. I went to my doctor's, and I was given another medication, which did help. However, it was a holiday, so the night it happened, I had nowhere to call apart from going to the emergency department. I am telling you this because I think you should state all the possible side effects on your medication on the enclosed leaflet or box. That way, an earlier diagnosis can be made."

• Pho...
• Taken for less than 1 month
• October 23, 2018

For Xerostomia "I started using XyliGel (my dentist gave me a sample), it works wonderfully. After using it for 4 days, my gums and teeth hurt. Last night, I had to get up and brush my teeth and use mouthwash because my gums hurt so much, I was getting scared. If I bite down on anything, my teeth hurt. I am so disappointed that I can't use XyliGel anymore, it worked so well for me. Something is very wrong. I've been reading reviews on this product, and a great many people are experiencing the same thing."

• gra...
• Taken for 1 to 6 months
• December 1, 2019

For Xerostomia "I have dry mouth due to Sicca syndrome, and at first, I thought it was wonderful in relieving dry mouth at night. Gradually over several months, I had gastric issues and sensitive teeth. I also had to have 2 root canals in previously good teeth (related?). When it got really uncomfortable, I visited my doctor due to black, gassy stools several times a day, terrible gas, pressure, and rumbling in the stomach. Then reflux started. Stool test and blood test were normal, so Dr. made an appointment with a gastroenterologist (not seen yet). I found a reference to gastric side effects from Xylitol. I stopped using the XyliMelts, and symptoms went away."

• Del...
• Taken for less than 1 month
• April 28, 2023

For Xerostomia "After being put on a CPAP machine, I purchased XyliMelts Dry Mouth Stick on Melts. The night I used them, I did experience significant relief from dry mouth. However, I ended up with two severe sores on each side of my mouth in the area where I used the product. It has been a week since I used them, and the sores are still painful and present. I have not used XyliMelts since then. What I find concerning is that although other people have reported this side effect, I cannot find any information from the manufacturer stating that it can cause mouth ulcers or sores as a side effect. The only mention I found was that a small number of people can be allergic to the adhesive and should buy the product with a different form of adhesive."

• Dia...
• Taken for 1 to 6 months
• March 15, 2018

For Mucositis "I was told by my dentist to use these or something like it for dry mouth. I did. They work great. Till they started eating my gums! I thought I had an abscess on one molar, then the other side flared up. Both in the same place I put the melts. Seeing my dentist next week. Hope there is no permanent damage."

• Kis...
• Taken for 6 months to 1 year
• August 7, 2013

For Xerostomia "I take Vesicare for an overactive bladder. It helps a lot, but the side effect is extreme dry mouth!! I tried Bioteen and didn't like the taste. I then tried TheraBreath lozenges which seemed to help, but I didn't like waking up in the night and needing to suck on a strong mint-flavored lozenge. When I tried Mouth Kote spray, I had instant relief, and it left no real bad taste in my mouth. The bottle is next to me at night, so when I wake up with a Sahara desert in my mouth, I simply spray a couple of times into my mouth, swish it around for 10 seconds, and fall right back to sleep."

• All...
• July 12, 2021

For Xerostomia "I’ve been using XyliMelts for several months, and they were great at first. It seems I have developed an allergy to them. My mouth became so irritated that it was hard to eat anything. The corners of my mouth were a mess too. I didn’t realize that it was the XyliMelts that was causing it until I stopped using them to experiment and see. Sure enough, the irritation stopped slowly. I won’t use them again. I’m so sad because they let me get a little sleep at night."

• Rel...
• Taken for 1 to 6 months
• January 21, 2013

For Xerostomia "I have a dry and painful mouth of unknown cause. I have tried Biotene mouthwash, the rubbery lozenges, and several other treatments, but finally found Mouth Kote. Clearly, it is the best for me. It has a lime (but not sweet) taste. It causes you to make saliva when spraying it in. I seem to be able to use it as often as I like. It really helps."

• spa...
• June 18, 2018

For Xerostomia "I have Sjögren's and loved XyliMelts as it meant I could sleep several hours without a drink. But had a side effect of diarrhea and didn't associate it with XyliMelts for 4 months even after other med changes and gastro tests. Eliminated them 3 weeks ago and no diarrhea, so xylitol was the culprit. Now thinking of trying Mouth Kote."

• Ann...
• Taken for 1 to 2 years
• December 7, 2020

For Xerostomia "XyliMelts was recommended by my dentist’s office for dry mouth caused by meds that I am on. Used nightly as instructed for 1 year. Decayed front tooth in my bridge & 3 teeth in my lower jaw. Having to get dental implants & already got 3 crowns in lower jaw. Cost approximately $7K. Wish I never heard of XyliMelts."

• Aly...
• August 7, 2016

For Xerostomia "Biotene went down my throat and fused my epiglottis shut so that I could not breathe. Finally freed it and developed pneumonia and spent three days in the hospital. I was told it had wax in it. Very dangerous. Deadly."

• ARP...
• Taken for 1 to 6 months
• February 23, 2023

"These definitely helped my dry mouth. But, I had to have a one-year-old crown on a molar replaced and a root canal and crown done on another molar on the other side of the mouth. Had infections under both molars. I am 81, always taken care of teeth, all of a sudden strange things going on. Will not be using XyliMelts again. My new dentist does not recommend them."

• Ngp...
• Taken for less than 1 month
• August 27, 2022

For Xerostomia "I have diabetes and started using these for dry mouth. My blood sugar hasn't been over 180 for a year. Within a few days of using these, my blood sugar was reading in the 250’s and higher, with no other changes in my life except for the xylitol. It doesn't make sense because there is no sugar in the product, and xylitol is not supposed to raise blood sugar, but there it is!"

• JLa...
• Taken for 2 to 5 years
• January 21, 2020

For Xerostomia "Have used XyliMelts for years for dry mouth at night. Definitely helps with sleep. Sometimes the area of the gum where I put the XyliMelts is a little sensitive, but worth it for the sleep. Have tried other products, but these are the best. I am 80 and developed this dry mouth at night about five years ago. No real cause determined. Discovered this product by trial and error. Dentists need to be informed. I told my dentist, and she now recommends this product."

• CPM...
• Taken for 1 to 6 months
• January 28, 2020

For Xerostomia "Been taking XyliMelts at night (1) for dry mouth due to breathing through my mouth while sleeping. I'm 66, and I have OSA. During dry winter months while sleeping, I would wake up with a terribly parched mouth several times a night. This really helps! Side effect - seems to act like a mild laxative."

• War...
• Taken for less than 1 month
• May 28, 2022

For Xerostomia "I thought they were great at first, but my tongue would be extra sensitive after using them. I stopped after a week or so, but my dry mouth kept me up all night recently, so last night I used another one. Today my tongue has little sores all over it, and it hurts to eat. I won't be using these again."

• TXT...
• Taken for 6 months to 1 year
• February 27, 2013

For Mucositis "I had horrible mucositis during my first round of chemo. I was hospitalized for 30 days. NeutraSal mouth rinse has kept me from ever getting a big outbreak of those awful sores again. NeutraSal has been a 'miracle' product for me."

• jan...
• Taken for 6 months to 1 year
• March 16, 2023

For Xerostomia "This caused major irritation on my tongue and in my mouth, similar to burnt tongue syndrome (yes, this is a real condition). I discontinued the product and found my tongue and mouth improved immediately, with the condition going away completely in a few days. I will never take this again. Other products work without terrible side effects."

• TDa...
• Taken for 1 to 6 months
• September 28, 2019

For Xerostomia "I've been using XyliMelts tablets for about one month since I started using the CPAP for sleep apnea to help dry mouth caused by the CPAP. So far, I have had only positive results. I wake up in the AM after a night's rest, and the tablet has dissolved. I may have to move my tongue around to completely spread the tablet, but the overall effect is positive."

• Joa...
• July 9, 2021

"I have dry mouth due to three different meds. Didn't know the damage dry mouth could cause other than needing to keep a bottle of water near at all times. One day, a tooth just broke off. The dentist showed me that my teeth were the consistency of chalk. She recommended a choice of three or four products. They worked as long as I had one in my mouth, but as soon as the substance was melted or gone, my mouth was dry again. I ended up losing another couple of teeth. My tongue looks like it has large cracks all over it. Even when the dentist is working in my mouth, she had to wet my tongue down every few minutes. Others think XyliMelts causes loss of teeth when it may be the dry mouth that causes it. That was my case anyway. Finally, another dentist recommended XyliMelts! It has made a huge difference. I have had no side effects. Thank you so very much. Had I discovered it earlier, I could have saved thousands of dollars, hours in a dentist chair, and several teeth."

• Bir...
• Taken for 1 to 6 months
• January 25, 2025

"I have had dry mouth since my insurance company stopped paying for the name-brand medication. I ended up with a bacterial infection in my mouth because of the lack of saliva. The dentist recommended Biotene products, which worked well but only while the product was in my mouth. I started using XyliMelts 2 months ago, 1 each night, and loved the results. I wear retainers that cover my teeth and parts of my gums, so I use wax to stick the XyliMelt to my retainers. Recently, I have noticed the XyliMelt has irritated my gum and my mouth, right where the XyliMelt was placed. My daughter had warned me about some medications that people place on their gums that have caused their gums to recede. I started placing the melt closer to the front of my mouth to note the condition of my gums where I place the melt. I think the directions to place it on a back molar is because the front of your mouth holds the melt too tightly, causing irritation. The melt was also more effective on a molar too."

• cam...
• Taken for 1 to 6 months
• October 22, 2024

For Xerostomia "I've had dry mouth due to a couple of meds I take. I was using a Biotene oral mouth rinse, which was somewhat helpful, and I could sleep through the night without having to get up for water about half the nights. After starting chemo, the nighttime dry mouth was even worse, and my dentist recommended XyliMelts. They are exactly what I needed, and I take them when I am exercising, giving a presentation, and at night. I use perhaps 3-4 within a 24-hour period. I also drink a lot of liquids and use a sugar-free throat lozenge as needed during the day. I haven't had any problems with them except a slight irritation where I was adhering the nighttime tablet, so I began to switch sides, which solved the problem. Now that I'm reading the reviews, it makes me a bit tentative. I have recommended them to others, but I'll be more wary about potential side effects, to be sure."

• Sea...
• Taken for less than 1 month
• January 5, 2017

For Mucositis "I bought a bottle of Biotene spray yesterday. At first, I was a little mad. It's a tiny bottle for like $6. I didn't even wait to get home; I opened it in the car. Worth. Every. Penny. I don't know what is in it, but it is amazing. In 0.02 seconds, my mouth went from feeling like the Sahara Desert to your next-door neighbor Jimmy's slip 'n' slide when he put the baby oil on it. Ok, all jokes aside. Immediately, your mouth feels better because it's all lubed up, but whatever is in it made me start salivating myself. And it tastes good too. The downside was it made my tongue swell, gave me those painful 'lie bumps', made my throat hurt, and hard to swallow. I must be allergic to something in it, but all is good over here. No regrets; would try again."

• MDD...
• Taken for 6 months to 1 year
• September 21, 2016

For Xerostomia "I actually liked this product when I was using it, but hated the inconvenience of having to mix the powder. It was hard to use away from home. My doctor gave me a lot of samples, but now he said it isn't available? Not sure why. I like a new product he gave me a sample of called Lubricity (it's an oral spray), and I love the convenience of it. It also seems to last considerably longer than NeutraSal and most of the other products I've tried. Unfortunately, it's not in any stores by me yet."

• Pat...
• January 15, 2017

For Xerostomia "I have Sjögren's, so I have a dry mouth. From the first time I tried it, I was impressed with no dryness from alcohol in my mouth, no burning. This mouthwash has kept my breath and mouth slightly moist for a while after use too. I highly recommend this for dry mouth, from medications or medical conditions."