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Keytruda and Pain: What Users Say

Pain: mentioned by 10 users (4.0%)

Based on user experiences from 253 Keytruda reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 12.3%
shortness of breath 7.1%
loss of appetite 6.7%
weakness 6.7%
tiredness 6.3%
diarrhea 4.7%
itching 4.3%
swelling 4.3%
cough 4.0%
pain 4.0%

Reviews for Keytruda

Commonly mentioned side effects
  • Wor...
  • Taken for 1 to 6 months
  • October 22, 2019

For Solid Tumors "DO NOT TAKE THIS DRUG! My mother was healthy before taking this drug. The drug caused her to stop walking, damaged her kidneys and liver, and caused fluid in her lungs. Her cancer spread to different areas of her body. Her red blood cells and platelets completely bottomed out in her last month of life and never came back to normal levels. She had severe rashes and pain. This drug shortens your life. This drug killed my mother!"

1 / 10
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  • Edd...
  • May 19, 2018

For Urothelial Carcinoma "My husband died right after the second dose. After the first dose, he suffered very badly for the next three weeks. He told the RN he was in pain, but she sent him for the next dose, and the very next morning he had severe pain all over, especially in his back. I read every comment here before my husband started Keytruda, but I wish I could understand this medication better. Now I know what this medication did to my husband. He lost his voice and couldn't sit, walk, talk, and he was just crying and asking what was going on? Why is this happening to me? Your loved ones could die worse than a death by cancer from cancer."

1 / 10
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34 Report
  • cab...
  • Taken for less than 1 month
  • May 24, 2018

For Non Small Cell Lung Cancer "My father-in-law took his first dose of Keytruda, and after a few days, he felt strong pain all over his body. His heart was beating out of control. After we took him to the emergency room and after all scans and tests, the doctor confirmed that it was a side effect of the Keytruda. After one day in the hospital, his heart was already so damaged that after less than a day, he passed away. This drug took his life. This drug needs to be taken out of use and reevaluated."

1 / 10
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Frequently asked questions

  • Not...
  • Taken for 1 to 6 months
  • September 16, 2021

For Non Small Cell Lung Cancer "My husband has stage 4 metastasized lung, kidney, and brain cancer. He started Keytruda in late May 2021. 3 1/2 months later he is in bad shape. Terrible shoulder pain. Confused. Tired. No appetite. Four hospital stays. Can't eat solid food. Lost 12 lbs in 5 days! Heart attack. Keytruda is so bad for my loving husband. Please research this deadly drug before you or a loved one is given an infusion. My husband is slipping away from me and his family."

1 / 10
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  • Sun...
  • Taken for 6 months to 1 year
  • October 30, 2020

For Melanoma "I started Keytruda in Feb 2020 for stage 3 aggressive melanoma. Almost immediately, my moods were awful. Swinging like a kid hitting puberty. The doc said it wasn't a side effect. This continued. The fatigue increased. I felt miserable. By late August, I couldn't get off the couch without moaning in pain and couldn't even get into bed. No appetite. Nausea. No energy. I knew I was dehydrated. I declined my next treatment and got fluids. I went to the next appointment to tell the doc I was quitting. Finally, they did labs. My cortisol was >0.1. Another lab test result had ridiculously low levels as well. I should've been in the hospital. Now I'm on steroids, was waiting to see an endocrinologist, and hoping there's no permanent damage. Keytruda almost finished me off."

1 / 10
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  • joh...
  • Taken for 6 months to 1 year
  • July 13, 2018

For Solid Tumors "My mother has been taking this for a few months, and she has completely changed. She suffers from extreme memory loss, confusion, body rashes, and now has to get fluids weekly because she sweats constantly. She has lost an insane amount of weight, lost all her muscle, and is shaky. Her body is in constant pain. She took a break from it for a few months, and during that time, she felt better, but her cancer came back. They say she will be taking this drug for the remainder of her life. 'It'll keep her alive,' but honestly, at what cost? This medicine has robbed her of her quality of life. I would never recommend this to anyone who is looking for healing. It does more harm than good."

1 / 10
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  • Eli...
  • Taken for 1 to 6 months
  • July 25, 2021

For Solid Tumors "This drug does not cure sacral tumor. My mom passed away after the fourth cycle of Keytruda. She lost a lot of weight and is always in constant pain. She couldn't eat and was always nauseous. She passed away two days ago, and she was 84."

1 / 10
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More FAQ

  • Lal...
  • Taken for 6 months to 1 year
  • January 5, 2020

For Non Small Cell Lung Cancer "My brother, a disabled vet who has smoked 4 packs a day since he was a teen, has Stage 4 SCLC. The VA Dr. gave him 9 months to live. Non-operable and no radiation offered. They offered him 8 Keytruda treatments, and the tumors did shrink. He’s done well except for horrible leg, feet, and especially knee pain, so bad he’s wheelchair-bound because he’s a fall risk. He is also a diabetic and schizophrenic. He’s been at the VA for over a year, and now they have moved him into the nursing home part. The problem is the nursing home part of the VA has not taken him for the Keytruda in two months. Nobody is telling him or me anything, and his social worker, that he got two months ago, has not reached out to either of us, nor have any of the Drs. Strangely enough, he is 63 and diagnosed with schizophrenia at 17. He has been a normal person, the brother I am now getting to know since being at the VA for over a year. He is still smoking 4 packs a day. No Drs are telling him what’s going on."

6 / 10
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  • Lal...
  • Taken for 6 months to 1 year
  • January 5, 2020

For Non Small Cell Lung Cancer "My brother, a disabled vet who has smoked 4 packs a day since he was a teen, has Stage 4 SCLC. The VA Dr. gave him 9 months to live. Non-operable and no radiation offered. They offered him 8 Keytruda treatments, and the tumors did shrink. He’s done well except for horrible leg, feet, and especially knee pain, so bad he’s wheelchair-bound because he’s a fall risk. He is also a diabetic and schizophrenic. He’s been at the VA for over a year, and now they have moved him into the nursing home part. The problem is the nursing home part of the VA has not taken him for the Keytruda in two months. Nobody is telling him or me anything, and his social worker, that he got two months ago, has not reached out to either of us, nor have any of the Drs. Strangely enough, he is 63 and diagnosed with schizophrenia at 17. He has been a normal person, the brother I am now getting to know since being at the VA for over a year. He is still smoking 4 packs a day. No Drs are telling him what’s going on."

6 / 10
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7 Report
  • Lal...
  • Taken for 6 months to 1 year
  • January 5, 2020

For Non Small Cell Lung Cancer "My brother, a disabled vet who has smoked 4 packs a day since he was a teen, has Stage 4 SCLC. The VA Dr. gave him 9 months to live. Non-operable and no radiation offered. They offered him 8 Keytruda treatments, and the tumors did shrink. He’s done well except for horrible leg, feet, and especially knee pain, so bad he’s wheelchair-bound because he’s a fall risk. He is also a diabetic and schizophrenic. He’s been at the VA for over a year, and now they have moved him into the nursing home part. The problem is the nursing home part of the VA has not taken him for the Keytruda in two months. Nobody is telling him or me anything, and his social worker, that he got two months ago, has not reached out to either of us, nor have any of the Drs. Strangely enough, he is 63 and diagnosed with schizophrenia at 17. He has been a normal person, the brother I am now getting to know since being at the VA for over a year. He is still smoking 4 packs a day. No Drs are telling him what’s going on."

6 / 10
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7 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.