Pembrolizumab User Reviews & Ratings (Page 4)
Brand names: Keytruda
Pembrolizumab has an average rating of 5.3 out of 10 from a total of 290 reviews on Drugs.com. 44% of reviewers reported a positive experience, while 44% reported a negative experience.
Reviews for Pembrolizumab
- Dee...
- May 10, 2018
For Non Small Cell Lung Cancer "My mom was supposed to have three infusions. After the first, she became ill with several side effects. She was so brave and went for her second one, two days later she was in the ER with a collapsed lung. Her health declined so rapidly, and she passed away one month later. I honestly feel it was the Keytruda, she would have lived longer without it. Please stay away from this drug."
- Sch...
- Taken for 1 to 2 years
- April 20, 2021
For Melanoma, Metastatic "Had stage 4 melanoma that presented in my scapular bone in June 2016. Operation to remove meant I lost some movement in my right arm. Six months later, it spread to the right femur bone and C3 in the neck. Started Keytruda in December 2016. Scan in March 2017 showed no evidence of any cancer. Four years later, living a normal life. Side effects minimal for the whole two years I was on treatment. Immune system kicked back into gear and did the job. Amazing drug as it doesn’t poison you like chemo. Highly recommend."
Frequently asked questions
- Pembrolizumab vs. nivolumab: How do they compare?
- What type of cancer is pembrolizumab used for?
- How are Inlyta and Keytruda used in kidney cancer?
- How does pembrolizumab affect the immune system?
- Maw...
- Taken for 1 to 2 years
- June 30, 2023
For Renal Cell Carcinoma "I don't know how much it has helped or not helped, but I do know that I've been on Keytruda now for 2 years and I don't have any side effects whatsoever. Thank you, Father. It looks like some people have. I started with renal cell carcinoma in my right kidney. They took out my kidney 9 years later. They found it had metastasized to my lung. I lost the lower left lobe of my lung. And I've been on Keytruda ever since, with Linvema in the evenings as a capsule. God willing, I am okay. Some lung issues while walking or in the sun but otherwise I am okay."
- Art...
- Taken for 6 months to 1 year
- October 13, 2018
For Head and Neck Cancer "I've been on Keytruda for eleven months now. So far, the growth has slowed to where we can call it 'arrested.' At least it has bought me another year of life. The side effects are manageable, for me at least, so I guess I'm one of the 'lucky' (I don't feel lucky having cancer to begin with) ones from reading the other reviews."
- Duz...
- Taken for less than 1 month
- November 6, 2020
For Non Small Cell Lung Cancer "My dad took this drug because they said his chances were good to prolong life. They said his body tested strong. He took one treatment and was joking around that day. He had almost every side effect within 5-7 days. We lost him within 2 months after this. He was so weak and frail. I don’t recommend it. I regret ever going this route."
- Nan...
- Taken for 1 to 2 years
- September 26, 2019
For Non Small Cell Lung Cancer "My husband, age 66, with lung epithelioid sarcoma stage 4. Rare form and aggressive. Keytruda caused hypothyroidism, weakness, aches and swelling in arms and legs, tingling and numbness in feet, severe mood changes. Yes, this Keytruda has helped him fight this cancer but at a cost to quality of life. It is wonderful to have him here with us after 20 months of battling this cancer, but it saddens me to see he cannot fully enjoy life. Keytruda also caused his eyes to blur and therefore he cannot read books, which he has always loved to do! At what cost shall we suffer just to stay alive? Not to discourage others from taking this drug, everyone reacts differently to drugs, and many can continue to support their families. But in my husband's case, he has the side effects listed on the website."
More FAQ
- How is pembrolizumab (Keytruda) administered?
- How does pembrolizumab kill cancer cells?
- Is lenvatinib / pembrolizumab used in endometrial cancer?
- What are biologic drugs and how do they work?
- The...
- Taken for 1 to 2 years
- January 27, 2020
For Melanoma, Metastatic "I have stage 4 melanoma and have just finished two years of Keytruda following a metastasis to my bowel. Thankfully, living in the UK, our NHS covered the cost of it. During this time, I had no side effects other than fatigue, which I managed at home. Recent scans have been clear, so for me, I am more than happy with this drug."
- Hea...
- Taken for less than 1 month
- October 5, 2022
For Renal Cell Carcinoma "My husband had lung cancer, for which he had radiation. Within 3 months, it metastasized to his kidney and spine, stage 4. He was in terrible pain, so they did 15 treatments of palliative radiation. After this, the oncologist encouraged him to try the Keytruda infusions. As soon as the infusion started, he said he knew it was a mistake. Upon completion of the treatment, he came out of the building disoriented. Two days later, he was in the ER with low calcium, low magnesium, kidneys failing, and dehydration. By Friday, he was under hospice care. It has been 2 weeks since the infusion, and he continues to spiral downward. Please, I beg you, don’t use this treatment. It is lethal."
- dru...
- Taken for less than 1 month
- July 31, 2020
For Urothelial Carcinoma "My brother, who was a healthy 70-year-old, was diagnosed with bladder cancer. After 6 chemotherapy treatments, which were somewhat beneficial, he was given one dose of Keytruda. Although his doctor told him, 'most of his patients don't have any side effects and if (he) did, it would be in 5-6 weeks.' Within two weeks, my brother ended up back in the hospital and passed away 5 days later. His records are clear in stating that the Keytruda caused multi-organ failure. He died 5 days later. Keytruda is a very bad drug and should not be available for use."
- Tes...
- November 17, 2017
For Non Small Cell Lung Cancer "My father had Keytruda, and now he is dead. Stay away from this form of treatment! It does not lengthen your life, it shortens it. It also stops all the good in your immunity. Please stay away from this drug!"
- bkc...
- Taken for less than 1 month
- December 8, 2022
For Non Small Cell Lung Cancer "Stage 1 lung cancer, surgically removed 3 years ago. No chemo or radiation. Clean lung scans for 3 years. No cancer in the lungs now. However, diagnosed with lung cancer brain mets. Whole brain radiation and Keytruda treatments. Prior to Keytruda treatments, the patient had NO need for supplemental oxygen. ZERO need for supplemental oxygen. Within 4 weeks and after only 2 Keytruda treatments, severe lung damage occurred. As with other reports here, high levels of oxygen are now required, and there is a continual severe drop in oxygen with any movement whatsoever. Sitting up in bed, shifting body to the side, reaching for something, causes severe drops in oxygen levels. Whether the lungs can be repaired or not is yet to be seen. I'm sharing this information with you and hope you will think long and hard before rolling the dice on this drug. The damage done is ironically somewhat more devastating than the cancer tumors in the brain. Think long and hard."
- Mad...
- Taken for 1 to 6 months
- November 3, 2021
For Non Small Cell Lung Cancer "My dad started Keytruda in March 2021. He had lung cancer. This was pretty much the only option he was given. He died very suddenly 3 months later. One day, he started having horrible abdominal pain. Took him to the ER, where he was admitted to the ICU. He had one kidney completely fail and 3 aneurysms. I feel had he not started Keytruda, he would still be with us."
- Not...
- Taken for 1 to 6 months
- September 16, 2021
For Non Small Cell Lung Cancer "My husband has stage 4 metastasized lung, kidney, and brain cancer. He started Keytruda in late May 2021. 3 1/2 months later he is in bad shape. Terrible shoulder pain. Confused. Tired. No appetite. Four hospital stays. Can't eat solid food. Lost 12 lbs in 5 days! Heart attack. Keytruda is so bad for my loving husband. Please research this deadly drug before you or a loved one is given an infusion. My husband is slipping away from me and his family."
- Key...
- June 18, 2020
For Non Small Cell Lung Cancer "I believe Keytruda killed my dad. After the second dose, he quit eating. He was getting sick, no energy. Doctors just kept saying it wasn't that and pushing the drug. He had a tumor that appeared and rapidly grew. Also, his best friend was on this for the same, and he is now really, really sick. This is a horrible, horrible drug and should be taken off the market."
- ege...
- Taken for less than 1 month
- August 13, 2021
For Non Small Cell Lung Cancer "My mother-in-law completed chemo and radiation for stage 4 lung cancer. Radiation helped a lot with brain and bone tumors. She did one treatment of Keytruda, her lungs became inflamed, and she died 10 days later. I believe immunotherapy is the future for cancer treatment after traditional options are used, Keytruda is NOT it."
- Pha...
- Taken for less than 1 month
- February 4, 2023
For Melanoma "My mother was diagnosed with a small area of skin cancer, despite feeling well. She maintained a positive attitude and began taking Keytruda three weeks ago. However, she was later admitted to the hospital due to difficulty holding up her head and fluctuating oxygen levels. After spending two weeks in the hospital, she was unable to eat and required a feeding tube. Sadly, she passed away last night at 10 PM. After reading reviews, it appears that many people have had negative experiences with Keytruda despite only being on the market for a few years. If you or someone you know has experienced organ damage as a result of Keytruda, it is important to seek medical attention and take action as needed."
- Dav...
- Taken for less than 1 month
- January 16, 2019
For Solid Tumors "My wife was given this drug as an option to help with her breast cancer, a week later, she passed into Heaven. We were both excited and hopeful for an immunotherapy drug like this, which did nothing to save my beautiful wife!"
- Red...
- August 5, 2021
For Melanoma "My husband had successful surgery to remove melanoma from his back together with three lymph nodes in December 2019. His oncologist recommended he do Keytruda immunotherapy as a precaution to ensure no additional cells were hiding in his body. He was not in favor of this, but both his oncologist and I encouraged him to proceed with the immunotherapy. After two or three treatments, he started having reactions to the drug and was put on steroids to counteract the reaction. After seven treatments, the immunotherapy was discontinued and health continued a downward spiral with numerous other reactions and in and out of the hospital due to the reactions. On September 25th, 2020, my husband passed away from pembrolizumab toxicity. We had received two sheets of paper advising of adverse reactions to this drug, but nowhere did it warn against death. Had it disclosed that it could cause death, I certainly would not have recommended that my husband be injected with this deadly drug."
- joh...
- Taken for 1 to 6 months
- October 2, 2018
For Head and Neck Cancer "Four injections so far on Keytruda as a first-line HNSCC treatment. No side effects. Approximately 70% reduction already in my left side face swelling, which is due to swollen lymph nodes that have been swollen for years. Three-month MRI due October 8, 2018, so too early to say anything about tumor response. Diagnosed six years ago but did no treatment until Keytruda as I did not want to do radiation in the oral cavity and was offered nothing else. I have found many sources indicating the patient must have an undamaged microbiome for the treatment to work effectively. Patients on previous platinum-based chemotherapies will have a weak microbiome. Action should be taken to restore the microbiome prior to starting immunotherapy."
- His...
- June 19, 2019
For Solid Tumors "My husband has stage 4 sarcoma (Lung Epithelioid Sarcoma, squamous cell carcinoma), a rare aggressive form. Appearing in lymph nodes around the lungs and adrenal gland. A large one between the heart and lung, a large mass located on his adrenal gland. Did chemo for 9 months. Tumors between the heart and lung and adrenal gland shrunk to 1/3 the size it was a year ago, has not touched the others around his lung, but the cancer remains stable. Keytruda is NOT without its side effects, he cannot focus to read much, moody for 2 weeks after treatments, then feels a bit better and it's time for another treatment. Seems like he has about 50% of the side effects listed, it also caused injury to his thyroid gland, and the doctor has increased levothyroxine 3 times in 2 months! Arthritis now in his hip and back. Bruising terribly, weakness, fatigue, headaches, insomnia, but he perseveres and forces himself not to give in. He is still here with us."
- Mic...
- May 14, 2020
For Small Cell Lung Cancer "After the first infusion, immediate aggravation of my arrhythmia to the point of having episodes daily unlike ever before. Developed a persistent cough which made speaking difficult. Also, shortness of breath. Mentioned arrhythmia to my oncologist who was not inclined to blame Keytruda for the increased frequency, although arrhythmia is a known side effect. Three weeks later, the second infusion, everything worsened to the point of debilitating weakness. Researching Keytruda, I discovered it is NOT the wonder drug touted by so many. A lot of side effects, failing health, and death. Prior to Keytruda, I experienced myself daily as healthy, although diagnosed with lung cancer and infrequent arrhythmia. Today, my quality of life is so little that I have decided to discontinue treatment. A third infusion might very well kill me. It's just not worth it. While Keytruda does seem to help some, it seems to injure many more, like myself."
- Big...
- Taken for 1 to 6 months
- March 25, 2021
For Head and Neck Cancer "After meeting with a surgeon who is the best, who advised me he could do the surgery. Yup, removal of my tongue, facial nerve damage with lifetime pain, feeding tube, and not being able to speak. I decided, “No thanks.” I like my tacos and being able to tell people I love them. My oncologist suggested Keytruda and immunotherapy. It saved my life and my tongue!!"
- Bar...
- Taken for 1 to 6 months
- May 24, 2022
"My husband went through 2 different sets of 7-week treatments of radiation for angiosarcoma and never had any side effects to speak of at all. Then a spot came up again on his head, so they put him on Keytruda infusions. He had 2 treatments 6 weeks apart. He got really sick the week before his next one was scheduled, so they postponed it. He slept the whole next 6 weeks, stopped eating, barely drinking, so weak he could barely walk and then stopped being able to move on his own, he was confused, and most days could barely talk. The only side effect we were told he would probably might have was diarrhea, which he was more constipated than anything. After 6 weeks, 7 doctors, 1 ER visit, he died at home. No one was ever able to help him even when we told everyone he was on Keytruda. I have no doubt that medicine killed my husband and now I live with the memories of watching him die, and no one was able to help him. Please don’t take this drug."
- Sur...
- Taken for 1 to 2 years
- November 4, 2023
For Breast Cancer "I was diagnosed with stage 4 triple negative breast cancer and told I had 6 months to live if I did nothing. I refused chemo but was a candidate for Keytruda and agreed to try it. Within 3 months, my cancer disappeared off my CTScan. 14 months later, and I am doing great. I am more tired recently, but that has been the biggest issue. I am going about my day and traveling. Without chemo, I'm really experiencing no serious side effects and look normal. I would not hesitate to recommend Keytruda. It's literally a life saver!"
See also:
More about pembrolizumab
- Check interactions
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
- Breastfeeding
- En español
For Non Small Cell Lung Cancer "I have had numerous treatments over the past 18 months. Now, these didn't improve my general health, but that wasn't very bad at any time. I have now had 4 treatments of Keytruda and find that my general health has improved. My energy levels have certainly risen, certainly not as much tiredness as before, like I can walk 3 miles most days without any bother. Previous to starting this treatment, I had great discomfort with fluid on my lung, this discomfort has now gone. I never had any side effects from getting Keytruda, me living a very normal life, long may it continue!"