Ospemifene and Cramps: What Users Say

• Swe...
• Taken for 1 to 6 months
• April 8, 2019

For Vaginal Dryness "I started this medication about 3 months ago, and it had taken that long for it to work on me. Then I realized I’ve gained 10 pounds in those three months, and the hot flashes are extreme, with lots of sweating. Yes, it did what it was supposed to do, but I feel bloated, fat, sweaty, and have experienced leg cramps. Bottom line, not for me."

• Jan...
• Taken for 1 to 6 months
• July 31, 2019

For Dyspareunia "At first, it was definitely helping with dryness. Then I was wetting my pants all the time, and I got a horrific yeast infection -- took three rounds of medication to fix it. I also felt stressed -- lack of energy and weakness. I didn't realize how bad that had gotten until I went off it. The yeast infection was the final straw. Then, after being off it for a week, ovarian pain began, and I now will need to get this checked off. I went through early menopause (46). I think I have exhausted all options for the pain at this point."

• Nor...
• Taken for 2 to 5 years
• December 10, 2020

For Dyspareunia "I've been using Osphena for several years, and it changed my life. I could not have sex after menopause due to severe pain, like broken glass. I've had no side effects, no weight gain or bloating. Some leg cramps are easily handled with Ca/Mg supplement. But in addition, my gyno has me using melted coconut oil on penetration. She said do not use OTC lubricants, as they have ingredients that are drying. I also used a vag dilator for a while, as my muscles were so tight from pain avoidance."

• Cat...
• Taken for 1 to 6 months
• December 18, 2019

For Vaginal Dryness "I am having horrible headaches, leg cramps, drenched in sweat to the point where I am waking up in the middle of the night dehydrated, fatigue, and had none of that before taking. It started about a week into taking the pills. I am going to stop immediately and search for an alternative."

• Ann...
• Taken for 1 to 6 months
• November 7, 2019

For Atrophic Vaginitis "When I started the Osphena, I felt better, the hot flashes were horrible. Didn't notice any difference in sex, still hurt. By the 3rd month, a slight headache constantly and leg cramps were bad. Called the doctor and stopped taking."

• Ann...
• Taken for 1 to 6 months
• November 6, 2019

For Atrophic Vaginitis "When I started the Osphena, I felt better, the hot flashes were horrible. Didn't notice any difference in sex, still hurt. By the 3rd month, slight headache constantly and leg cramps were bad. Called the doctor and stopped taking."

• Cal...
• Taken for 2 to 5 years
• January 20, 2023

For Vaginal Dryness "I have been taking this for 3+ years, hoping to experience less painful intercourse. I cannot detect any benefits of taking Osphena, and after reading reviews, I am wondering if my severe hot flashes, night sweats, leg cramps, fatigue, and weight gain are related. I'm stopping this drug today. It may not be causing all of the above symptoms, but it certainly isn't providing any detectable benefits. I'm done."

• Mia...
• Taken for 1 to 6 months
• June 16, 2020

For Atrophic Vaginitis "I used this for only two months, had horrible bloating and leg cramps. I stopped. It did help a tremendous amount with the dryness, but the cramps just weren't worth it. They were several times a day!"

• DDa...
• Taken for less than 1 month
• August 6, 2020

For Atrophic Vaginitis "The side effects from Osphena are not worth the minor results. Overwhelming bloating and cramps."