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Glipizide User Reviews & Ratings (Page 2)

Brand names: Glucotrol, GlipiZIDE XL, Glucotrol XL

Glipizide has an average rating of 6.3 out of 10 from a total of 70 reviews on Drugs.com. 49% of reviewers reported a positive experience, while 29% reported a negative experience.

Reviews for Glipizide

  • 50-60...
  • Taken for less than 1 month
  • October 11, 2015

For Diabetes, Type 2 "I've had Type II diabetes. My doctor recently put me on Watson 461 Glipizide ER. Glucose levels came back under control. After this the pharmacy switched me to a "normal" release form. I experienced terribly shoulder aches which woke me up in the middle of the night. I thought these were due to a visit to the gym, but I have been doing exercise for the past 3 years without pain this bad. It took me a while to realize this is what happened when a previous doctor also put me on Glipizide, which resulted in the same excruciating shoulder pain. I've stopped using the medication, and the pain has decreased significantly (I am not woken at night with the excruciating pain any more, pain is still there in the background). Blurry vision too."

1 / 10
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61 Report
  • Kelly...
  • July 21, 2010

For Diabetes, Type 2 "I've found this to be the best diabetes medicine I've used. In the extended release version it provides consistent and significant reduction of blood sugar readings. My A1C dropped two full points with this medicine alone."

10 / 10
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82 Report
  • Gamer...
  • Taken for less than 1 month
  • October 2, 2014

For Diabetes, Type 2 "After having a severe reaction to Metformin, the doctor put me on Glipizide. While I don't faint on this medication, the side effects have been horrible for me. My sugar does seem to be better after being high for so long, it's finally below 160 most of the time. However, I am severely dizzy and foggy-headed constantly, to the point I stopped driving. Also have bad lower back ache, nausea, stomach upset any time I eat, blurry vision (I have perfect vision so this bothers me), and I've noticed some changes in my emotional response to things as well, such as anger and a bit of depression - which I've never had. The effects have been bad enough that I've had to take off work several days in a row as well as miss school."

5 / 10
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62 Report
  • Emmit...
  • September 10, 2017

For Diabetes, Type 2 "I have been on juniva and metformin for years. It has kept my weight and sugar levels between 91-135. For some reason my doctor decided to take me off that medication and put me on glipizide. In one month I had gained 15 pounds and my blood sugars were in the high 100's low 200's. After two months she decided to switch me back on to juniva. A bit late I think by blood sugar is now up into the 300' reds' and I have packed on another 15 pds. The glipizide ruined my blood sugars and an extra bonus it made me gain weight. DO NOT TAKE GLIPIZIDE FOR A FIRST SECOND OR THIRD CHOICE. TRY EVERYTHING ELSE FIRST!!!! There's no out of pocket experience but you pay dearly with your health."

1 / 10
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47 Report
  • bigbo...
  • April 16, 2011

For Diabetes, Type 2 "I'm male, 52, and have been a diabetic for 11years. For eight of those years I was prescribed glipizide, and it worked very well for me in keeping my glucose levels under control. The only adverse side effect that I experienced was sensitivity to the sun and to my computer screen. Sunscreen lotion with SPF 30 protection solved that problem. A new PCP tried to switch me to metformin, but I was intolerant to that medicine (bloating and diarrhea)."

9 / 10
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77 Report

Are you taking this medicine?

  • Jim...
  • Taken for 1 to 6 months
  • June 10, 2017

For Diabetes, Type 2 "Diagnosed with Type 2 diabetes, two years ago. My A1C 11.9 and 850MG Metformin prescribed which worked OK. 2 weeks blood sugars were 155. Fast forward 20 months blood sugars rockets to 300, then one night 500! Dr says try 1000 mg metformin and I'm down to 300. New Dr. Try Glipizide, 1 week blood sugars 170/ then 135/ now 105!"

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43 Report
  • BKano
  • Taken for 10 years or more
  • February 13, 2019

For Diabetes, Type 2 "Was at doctor yesterday, because my sugars are wacky, so the doc put me on Metformin 500mg take 2 in morning and 2 at night. Also on Glipizide 10mg 2 in the morning and 2 at night. I have the diabetes diarrhea too, off and on, and it is stressful going somewhere and have to find a bathroom. I would a preferred the doctor to put me on insulin, since I have to also take dozens of other meds. This is so depressing."

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33 Report
  • Kermi...
  • Taken for 1 to 6 months
  • March 31, 2016

For Diabetes, Type 2 "Within a few days of starting on a daily dose of 5mg I began having gas to the point that it was embarrassing and had trouble falling asleep every night. Gave up on Glipizide after a month and focused on eating better and getting more exercise instead."

5 / 10
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42 Report
  • Clay_...
  • Taken for 1 to 6 months
  • December 12, 2017

For Diabetes, Type 2 "I was diagnosed with Type 2 diabetes 1.5 months ago. My A1C was 15.8, Urine Glucose over 500 (test max) and my first home blood glucose test was 577. My doctor had me start with one metformin 500mg ER tablet a day for the first week, then two a day since then. I also was prescribed a 5mg tablet of glipizide a day. My Blood Glucose has been in the 85-150 range the past month. I have modified my diet some. I did experience some diarrhea, though am over it now."

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31 Report
  • DLE
  • August 23, 2017

For Diabetes, Type 2 "Am a 34 year old male. Diagnosed with Type 2 in April of 2016. Beginning A1C was 8.4. After a horrible start on metformin (gastrointestinal issues), was put on Farxiga 5mg. Using that alone brought me down to a 7.6 in August of 2016. MD upped the Farxiga to 10mg. That only brought me down to a 7.5 in April 2017. MD added Glipizide 2.5mg XL once a day with the Farxiga. Brought my a1c down to a 6.0 in August 2017. The drug combo of these two is working very well for me. The Glipizide has given me that extra kick to get things under control."

9 / 10
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32 Report
  • Angela...
  • Taken for 1 to 2 years
  • February 25, 2018

For Diabetes, Type 2 "I was put on Glipizide because the tier for victoza changed and it costed $400.00. Since being on Glipizide, my blood sugar would drop after an hour of taking it even when I take it with food. I didn't like the way I felt and if I had to leave the house, I wouldn't take it at all. I went back to using the Victoza I had left and I felt much better. I am now out of Victoza, but I refuse to go back to Glipizide. I'll try diet and exercise to lower my A1c"

1 / 10
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27 Report
  • Sugar...
  • Taken for less than 1 month
  • September 15, 2017

For Diabetes, Type 2 "I just started using glipizide 5 mg 3 weeks ago in combination with metforming 1000mg twice a day. It is a powerful medicine as I noticed my sugar was 300 and 3 hours later it was down to 100. My body was shaking and my stomach was not feeling well. I was told to take medication and eat 30 minutes later and then take metforming after meal. Since my numbers didn't go much over 150 doctor said we didn't need to up to the 10mg a day she thought I would need after the 3 weeks. I was avoiding insulin and was prescribed glipizide, I realize I must start doing it without it. Just use one medication or my stomach will suffer. I had a belly ache and later had to go to the toilet. I also have headaches and need more lotion since I am itchier."

10 / 10
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28 Report
  • Tumbl...
  • Taken for 5 to 10 years
  • July 30, 2019

For Diabetes, Type 2 "When I first started taking this med it worked. As time has passed I have had to take more of it to get a semi-desired result. Perhaps my body is adapting to it and has built up a tolerance. I don't know."

3 / 10
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22 Report
  • Becca
  • Taken for less than 1 month
  • January 10, 2016

For Diabetes, Type 2 "Type 2 since 2008 and started on metformin with great results. Over the years the metformin has been progressively increased to the max dose to maintain my A1c at <7. Metformin has now lost its effect and my last A1c was 10.1. Doctor discontinued the metformin and started Januvia 100 mg and Glucotrol xl 2.5 mg, gradually increasing to 20 mg/day. Nothing! The new combo has had absolutely no effect on my blood glucose levels. My FBS are >170 every morning and 2 hr PP around 240! My next drug is the non-insulin injectable, Victoza. I so wish it could be different."

1 / 10
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33 Report
  • RDWP
  • May 27, 2015

For Diabetes, Type 2 "I take a glipizide /metformin combo and have no stomach problems on it. It does quickly lower blood sugar sometimes to hyperglycemia numbers. I was on Glumetza a metformin hcl , coated tablet, non generic, very expensive almost $170.00 per month which had no gastric side effects because it is made by a company that specializes in gastro medication."

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34 Report
  • DayStar...
  • January 27, 2015

For Diabetes, Type 2 "I have been a Type 2 diabetic since 2007. I take Glipizide which is very effective at keeping my blood sugar levels down. But everyday it gives me an upset stomach and diarrhea which has me miserable. Just yesterday I had to stop what I was doing and rush home to the toilet. Horrible! Just imagine having terrible stomach pains and diarrhea everyday! It wasn%u2019t until recently that I realized this was a side effect of the Glipizide. I thought it was from foods containing Gluten that I have been eating. I had tried Metformin and that is just as bad. I%u2019m in the process of asking my doctor if there is something else I can take that won%u2019t upset my stomach so much. Right now I%u2019m in between jobs but need to get back to work! It%u2019s hard to"

8 / 10
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31 Report
  • Debtanz
  • October 7, 2020

For Diabetes, Type 2 "I was on a sliding scale of Novalog and then Tresiba @ night .. then I was also on Actos30 mg. Since Actos is a black list Med and can cause bladder cancer, I decided to try Glipizide 5 mg. Well—- for the first week, I could only take 1/2 of the 5 mg. So the dr said take 2.5 ( half the pill) I couldn’t sleep @ night up checking my BS because even the 2.5 plummeted my BS and I felt I had no control once I took the pills. It made me feel so bad with excitement, nervousness, & pain down my left arm. I do workout so this Med was too dangerous for me as I live alone snd these episodes were scary! I felt so bad. Took my last 2.5 & can’t wait till this medication is out of my body. Still have residual.. I’m back to my regime of sliding scale.. I’m done."

1 / 10
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14 Report
  • madan...
  • Taken for 10 years or more
  • February 15, 2018

For Diabetes, Type 2 "This seems to be a good drug . I take 10mg tablets twice daily along with metformin 1000mg morning and 500 mg evening, I am running 78 and morning bp reading is 150/85 and am satisfied and feel comfortable"

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20 Report
  • tudy
  • Taken for 1 to 2 years
  • July 20, 2021

For Diabetes, Type 2 "I have been on metformin for a few years, blood sugar was not as it should be so put on Glipzide, a year ago. I was put in hospital due to asthma they found I had very low sodium levels, My sodium levels have continued to fall and now 125, taken off Glipzide and so far sodium levels are increasing to 128, not normal but, at least I have hope. I have had horrid pain in my legs and back, at times I stumble and this all started when I went on Glipzide, Used to walk over 10,000 steps day, now my feet and my legs hurt so bad I can't walk any distance at all."

4 / 10
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9 Report
  • Robimat
  • Taken for 1 to 2 years
  • November 16, 2021

For Diabetes, Type 2 "Works very well in lowering glucose levels; however, significant side effects. Substantial weight gain regardless of diet/exercise, stomach pain, nausea, bloating, burning/tingling sensation in hands/feet all of which remit when the drug is stopped. I give a rating of 5 due to fantastic effectiveness at lowering glucose, but the side effects can be substantial."

5 / 10
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8 Report
  • Night...
  • Taken for 6 months to 1 year
  • August 21, 2021

For Diabetes, Type 2 "Been on glipizide er 2.5 for about 9 months. In the beginning it helped, sugar was 100-118, but the side effects were very bad. Every bone, joint, muscle in my body hurt. I have other health issues, uncontrolled B/P and this medication just made that worse. Stopped taking glipizide and the pains went away. When the pain started my sugar started to go to 160-189. Not a good medicine if you are on other medication. Dr’s don’t know everything and everyone is different and dr’s need to understand this."

1 / 10
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7 Report
  • DDoug
  • Taken for 6 months to 1 year
  • February 7, 2024

For Diabetes, Type 2 "At 79 years old, I have had Type II for 25 years. For years, I had loose stools with metformin but was never told that metformin may be the problem. My former doctors slowly reduced the dosage from 2000 mg daily down to 500 mg daily. The loose stool problem got better but my A1c kept slowly increasing. My new doctor put me on 10 mg daily glipizide and weekly Trulicity. The results were remarkable and quick. No more loose stools, but more importantly, my A1c reduced from 8.1 to 6.7 in three months and then down to 6.2 in six months. I call glipizide my miracle drug."

10 / 10
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1 Report
  • rich
  • Taken for 2 to 5 years
  • September 3, 2022

GlipiZIDE XL (glipizide) for Diabetes, Type 2 "I have been taking Metformin (2×1000) and Glipizide 2.5 for two years and been able to keep my A1c to between 6.2 and 6.4. Trying to watch what I eat and get some exercise. No side effects. Working for me."

10 / 10
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4 Report
  • yaban
  • October 28, 2008

"I've been taking Novomix and I had to go abroad. So I asked my doctor subtitude for Insulin because my blood sugar levels were between 190-250. He suggested glipizide and now my counts are between 115 - 120. I hsve now been taking glipizide nearly for a month. I eat less than usual and I exercise. "

8 / 10
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19 Report
  • Flinxx
  • Taken for 2 to 5 years
  • May 7, 2023

Glucotrol (glipizide) for Diabetes, Type 2 "I've used it for a couple years. It has brought down my A1C. It really highlighted my bad eating habits though. I tend to go long periods without eating. Doing that with Glucotrol leads to hypoglycemia. I end up with hypoglycemia pretty often. But that is from my own bad habits. Especially while I am in school. I am getting to the point of having to write 4 paper a semester and that is just going to get worse as papers are required to have more content. I intend to talk to my doctor about the new Glucagon-like peptide 1 (GLP-1) receptor agonists and Sodium-glucose co-transporter 2 (SGLT2) inhibitors. Especially the GLP-1 receptor agonists. They supposedly slow down the emptying of the stomach. I see food I just ate a couple hours earlier in my stool. That is way too fast."

10 / 10
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2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.