Replens and Swelling: What Users Say

• Bre...
• April 3, 2021

For Vaginal Dryness "Oh, how I had wished I had read the reviews here FIRST! I was diagnosed with vaginal atrophy, but the doctor recommended Replens. Tried the inserts first, all they did was swell me up with 0 lubrication. External gel - same swelling, but this time horrible burning and pain while urinating. It made me itch and burn like a yeast infection. Inside looked as bad as it felt. Decided to try the lubricant in the little packet that came with the inserts. It helped at first, but then - BAM! Soreness, itching, and painful urination with swollen labia internal AND external. On a whim, I took Benadryl, thinking this has GOT to be a bad allergic reaction. Benadryl took away the feeling of being on fire down there a little to save my sanity! I'll take dryness over this ANY day! Definitely need to report your reactions to the FDA!"

• Ann...
• Taken for less than 1 month
• October 17, 2021

For Vaginal Dryness "Be very wary when using this product. As per many of the ladies on this forum, I have experienced a really bad reaction to this medication and wish I had seen these reviews beforehand. I was diagnosed with severe vaginal atrophy in July, and the first round of HRT has not worked yet, nor estriol pessaries or cream from the Gyn. The GP recommended Replens. Total disaster - horrible burning and pain while urinating. Already had the start of a UTI, which compounded the situation. Inside looked as bad as it felt. Soreness, itching, and pain with swollen labia, internal AND external. I have also had the white clumpy residue. I wonder if that is related to the cramping. I will never use this again and will need to find out how to report these issues. If this product helps someone, then that’s great, but the majority of us are in worse shape from having tried this. If I could rate this 0 or a minus rating, I would. This product should be pulled from circulation."

• Jod...
• February 2, 2020

For Vaginal Dryness "1st time I used this product before sex. I was impressed with how comfortable the sex felt, but the horrible rubbery white discharge after was so embarrassing. The leaflet says to expect dry skin to be expelled, so I hoped it was a one-off. The second time I tried it, it caused severe burning pain for several hours and swelling. What a shame. I can’t risk trying it again."

• Est...
• Taken for less than 1 month
• July 12, 2024

For Vaginal Dryness "I’m 32. Never experienced vaginal atrophy. Stopped taking birth control and the changes started to happen. Initially thought it was a yeast infection. Treated twice and still no resolve to the dryness, itching and inflammation. I finally see a doctor who recommends Replens and I start to have the white thick chunky discharge, which are dead skin cells shedding, and then thick gooey bloody discharge only once. But my symptoms improved dramatically. The discharge did stop and I started to notice normal discharge and normalcy completely after 3 uses. It’s a godsend."

• She...
• Taken for less than 1 month
• October 6, 2021

For Vaginal Dryness "Absolutely shocking!! I am swollen and on fire inside and outside, labia is swollen. This is the second time I’ve used it, first time same thing, thought I had inserted it incorrectly, but no, same thing second time. Can hardly keep my legs together!! This product needs to be taken off the shelves, not even going to go there with the white clumps, it’s painful and shocking!!!!!"

• Fir...
• Taken for less than 1 month
• November 11, 2021

For Vaginal Dryness "I’m type 2 diabetic and it causes me to be dry. Tried this 1x and now I feel like something was seriously wrong! Thought I had an infection, but it’s a reaction to this stuff. Swollen inside and out, feel raw with burning, and urinating is very painful. Will not use again."

• No ...
• Taken for less than 1 month
• June 11, 2022

For Vaginal Dryness "Used this just once, and it might have relieved some dryness, but 2 days after using, experienced severe cramping, itching, and swelling, and white clumps coming out. Resorted to trying to rinse it out and using my finger to scoop some of the disgusting clumps out. Will never use this product again, remaining tubes now in the bin."

• DMA...
• Taken for 1 to 2 years
• June 15, 2023

For Vaginal Dryness "During 10 months of use, I started to experience severe bloating over the past 2 months, some burning, swelling, and just recently cramping on and off. Also, white discharge is more frequent. I too wish I had read these comments sooner. I used it yesterday and will never use it again. The product needs to be improved or taken off the market. I also thought that I had a UTI a while back, and other times, and tested negative with urinalysis and culture each time. I'll continue with external gel HRT."

• Lis...
• Taken for less than 1 month
• February 2, 2019

For Vaginal Dryness "I used this product, and I had a bad reaction. It caused burning, swelling, split skin from peeling skin, and strange white discharge."

• Hon...
• Taken for 6 months to 1 year
• December 24, 2020

For Vaginal Dryness "I use for vaginal dryness, and it causes swelling on the outside, so I will have to quit using it."