Replens and Discharge: What Users Say

• Sea...
• Taken for less than 1 month
• November 12, 2020

For Vaginal Dryness "I was recommended by a gynecologist to use this product Replens. Second time using it, I feel dry, and clumps of white skin cells or whatever it is have been discharging. I want to know if this is safe or a good thing. Adding to my frustration!"

• Ech...
• Taken for 1 to 6 months
• June 8, 2020

For Vaginal Dryness "I started using Replens as my gyno suggested for vaginal dryness/atrophy in March 2020. No negative reaction at first, with the exception of clear discharge. It is now June 2020, and I noticed I've been experiencing slight cramping like I'm going to get a period. I'm in my 60s and post-menopausal. Yesterday, I noticed a brownish discharge and still experiencing slight cramping. Will stop using Replens product immediately! I think further research and investigation into the product should be put in place, pronto. Too many women are having too many strange and unexplained reactions to this product. FDA should be alerted - NOW!"

• Ech...
• Taken for 1 to 6 months
• June 8, 2020

For Vaginal Dryness "I started using Replens as my gyno suggested for vaginal dryness/atrophy in March 2020. No negative reaction at first, with the exception of clear discharge. It is now June 2020, and I noticed I've been experiencing slight cramping like I'm going to get a period. I'm in my 60s and post-menopausal. Yesterday, I noticed a brownish discharge and still experiencing slight cramping. Will stop using Replens product immediately! I think further research and investigation into the product should be put in place, pronto. Too many women are having too many strange and unexplained reactions to this product. FDA should be alerted - NOW!"

• WAN...
• Taken for less than 1 month
• October 7, 2020

For Vaginal Dryness "Severe vaginal dryness after menopause is horrible. The vaginal changes can mimic UTI. Replens is the only thing that has given me relief. I use it every 3 days at night. If I get dry in between, I apply a bit by hand. I would rather feel wet and messy than dry as the desert. I did have some brownish discharge once after the first use, but it went away. I recommend because I suffered horribly before I used it."

• She...
• Taken for 1 to 6 months
• January 28, 2021

For Vaginal Dryness "After using Replens I experienced the white chunky discharge many people are complaining about. But after a few consistent uses I noticed that not only was the discharge turning a very dark brown, but I wasn’t coming out anymore! I had to manually get inside my vagina to pull out days of old, dark, chunky discharge. It had little to no smell to it, but was still very unpleasant to see. There’s no need in shedding dry vaginal tissue if the discharge is just going to stay inside the vagina! Never using it again."

• Jaz...
• Taken for less than 1 month
• October 4, 2020

For Vaginal Dryness "I have used Replens 3 times. I was crampy the first time. Felt like an oncoming UTI after the second insert. Then the white wet tissue discharge after the third time. Done... was not cheap, so a waste. Too many ladies seem to be having the same symptoms. Like others, wish I had read these reviews! Just don’t..."

• Anonymous
• Taken for less than 1 month
• August 2, 2020

For Vaginal Dryness "I just hope that someone is reporting these reviews to Replens. I've experienced everything from the chalky substance to a brownish discharge, which I believe to be a blood residue. It was a scary experience, as opposed to being helpful. Replens, go back to your lab and do something about this, please!!"

• Ssv...
• Taken for less than 1 month
• April 16, 2019

For Vaginal Dryness "I bought this product to try for my vaginal dryness. One hour after I used it, I started having a lot of gooey thick bloody discharge. I had a hysterectomy 15 years ago, and I am at the end of my menopause, so I am not sure why I have blood-stained underwear and this bloody gooey discharge."

• Jul...
• Taken for 1 to 6 months
• July 21, 2018

"Replens was recommended to me by my gynecologist for vaginal dryness/atrophy. Although it provided relief, the day after inserting it, I developed this very strange white, tissue-like vaginal discharge, together with burning and redness. The doctor said that my symptoms were not from the Replens, so I continued using it, but the side effects continued. I have since learned that the tissue discharge is a common side effect for many women."

• Lin...
• Taken for less than 1 month
• January 11, 2021

For Vaginal Dryness "Tried Replens one year ago for vaginal dryness due to menopause. (I'm 54.) Had a large amount of white, clumpy, rubbery discharge. Stopped using it after one week. The discharge is a mess and also a turn-off during sex. At least for me, it is. I use a low-dose estrogen and thought a moisturizer would complement that. It did not. I tried it again this week and used it twice, and the same issue: the white discharge. It's severe enough that I'm not using it any longer. Threw the tube away - total waste of money. It doesn't make any sense that this product should cause this much of an issue for myself and others. Honestly, I don't know why my gynecologist would recommend it?"

• Dma...
• Taken for 1 to 2 years
• May 6, 2019

For Vaginal Dryness "I decided to use Replens since I'm past menopause and don't use HRT. It's definitely helped with vaginal dryness and intimacy. However, lately I've noticed some discharge similar to yeast. I'm not sure if it's from the product or not, since I have no other symptoms. Upon reading some of the reviews, I do see that it is not uncommon. I'm going to purchase an over-the-counter yeast tester just to be sure, though. But do believe it's from the product."

• Do...
• Taken for less than 1 month
• October 12, 2022

For Vaginal Dryness "I was just getting over a severe yeast infection and was feeling better. I noticed some dryness and decided on this product. Holy moly!!! The clumps of white discharge (I had to scrape off with my finger) and the burn!!! What?!! I was freaking out thinking my YI was back with a vengeance until I read all the comments. How is this still on the market?!!!! We should all sue!!!"

• Dev...
• Taken for 6 months to 1 year
• June 23, 2021

For Vaginal Dryness "This stuff has totally changed my life, it works so well. I was in such discomfort, and my sex life was going down the drain after my hysterectomy. It works amazing and truly does last 3 days for me. That is the only downside: was the discharge at first, but it gets better."

• Mab...
• Taken for less than 1 month
• March 15, 2021

For Vaginal Dryness "After feeling like I had a constant yeast infection and irritation after sex, I realized it was dryness. I'm 43, had a hysterectomy 6 years ago, and suffer from Sjogren's syndrome. I tried Replens. The first dose, I had huge, white clumps that looked like wet toilet paper. Thought the second dose would be better, it wasn't. Two weeks later, I noticed blood clots and bloody discharge. Feels like I have a period again. Will not use again."

• Anonymous
• Taken for less than 1 month
• July 20, 2020

For Vaginal Dryness "One star! I had the white, clumpy discharge and awful skin irritation. I’m not sure why my gyno recommended this product, but the side effects aren’t worth it, and I’m not sure it did much for my dryness."

• Per...
• Taken for less than 1 month
• September 12, 2021

For Vaginal Dryness "Really interesting to read these reviews. I’ve been using it for the last few weeks, every 3 days. I’m loathing the white, tissuey discharge, which, as others have said, you literally need to scrape out yourself. The sight of it on my partner after having sex: mortifying. I’ve also had burning and awful cervical cramping and shooting pains, far worse than during a period, and some brown discharge. I’ve been blaming it on an endometrial biopsy I had a month ago, yet the cramping symptoms are repeatedly clearing by day 3, but coming back with a vengeance as soon as I use the product. I’m giving up, which is such a shame, as it gives a midcycle, ovulatory-feeling discharge, but every day."

• con...
• Taken for less than 1 month
• June 2, 2021

For Vaginal Dryness "I used 1/2 a dose the first time. Ended up at MD with a yeast infection and BV. Stay away. It has mineral oil and glycerin. Lesson learned. I should give my medical bill to the company. I am going to return if I can for sure."

• Mg6...
• Taken for less than 1 month
• June 19, 2021

For Vaginal Dryness "I too wish I had read these posts! I started taking Replens on the advice of my GP at the same time I was taking antibiotics for a UTI. Two days after I finished the antibiotics, I used another dose of Replens (every 3-day dosage) and felt cramping and bloated. The next day I had vaginal itching. The following day I experienced itching and burning, so I thought it was a yeast infection due to antibiotic use (even though I took probiotics). So I used an over-the-counter yeast medication. But I'm still having the cramping, also the brown discharge and now white discharge. I will see my MD if it doesn’t go away. I had taken 4 doses of Replens."

• Mg6...
• Taken for less than 1 month
• June 19, 2021

For Vaginal Dryness "I too wish I had read these posts! I started taking Replens on the advice of my GP at the same time I was taking antibiotics for a UTI. Two days after I finished the antibiotics, I used another dose of Replens (every 3-day dosage) and felt cramping and bloated. The next day I had vaginal itching. The following day I experienced itching and burning, so I thought it was a yeast infection due to antibiotic use (even though I took probiotics). So I used an over-the-counter yeast medication. But I'm still having the cramping, also the brown discharge and now white discharge. I will see my MD if it doesn’t go away. I had taken 4 doses of Replens."

• Mel...
• Taken for 1 to 6 months
• July 6, 2021

For Vaginal Dryness "Try it. Yes, you may have the “white discharge” (skin sloughing), but this product has been a big help for me. Have suffered with dryness for years, and this is the only thing I have found that consistently helps. I paid a lot for the Mona Lisa treatment and was disappointed."

• Jo5...
• Taken for 1 to 6 months
• May 17, 2023

For Vaginal Dryness "I am so glad to hear that I am not alone in my negative experience of this product. I thought it might help me enjoy sex with my husband again after menopausal dryness, and it did at first (I used it for just over a month), but then I got a UTI. Antibiotics took away the infection, but not the pain on urinating, which sometimes lasted for a long time after. Then on the 5th use, when my husband and I had sex, it was uncomfortable for me, and so we stopped. When he withdrew, he had these white clumps on him, which came from me. The white clumpy discharge continued, so I had a thrush treatment, which didn't work. Found out that Replens MD can cause these symptoms. I stopped using two weeks ago. Clumpiness stopped within days, still having pain on weeing, but it is lessening in severity and frequency, so hopefully it will go completely now I'm not using this stuff. I definitely would not recommend it."

• Whi...
• Taken for 1 to 6 months
• February 23, 2021

For Vaginal Dryness "I’m so glad to have found that others have had issues with this. It came highly recommended. I’m only 34 but have had a full hysterectomy due to uterine cancer. Each time I have tried using this stuff to treat vaginal dryness, it BURNS. Not sure a little sting, it feels like an acid burn for a good hour or so. After using it this last time, I’ve developed an infection and discharge, which I’ve never had before. I’ll definitely be discontinuing use of this."

• JJa...
• March 6, 2021

For Vaginal Dryness "I got a large amount of white, clumpy discharge within an hour of using. This residue comes out during sex and all over toys. Such an embarrassing turn-off, and I had to explain what I found out about the product so my partner didn’t think I was infectious or something. Will not use again and will notify my gyn so they don’t recommend. So gross! Was hoping it was a long-lasting product, and it is in a bad way."

• Gay...
• Taken for less than 1 month
• October 17, 2022

For Vaginal Dryness "Avoid this stuff at all costs! I was looking for something to help with dryness and burning caused by perimenopause. I used this twice and had a lot of watery discharge at first. I had sex the following day, and afterwards I had brown discharge. I had to insert and remove 3 tampons in a row to pull this stuff out, adding to the discomfort. I then started to get greyish discharge with black specks, burning, and cystitis feelings. I feel right back to square 1 with my symptoms, which were improving with Vagifem. I’m terrified about what I’ve done to my insides!"

• Gay...
• Taken for less than 1 month
• October 17, 2022

For Vaginal Dryness "Avoid this stuff at all costs! I was looking for something to help with dryness and burning caused by perimenopause. I used this twice and had a lot of watery discharge at first. I had sex the following day, and afterwards I had brown discharge. I had to insert and remove 3 tampons in a row to pull this stuff out, adding to the discomfort. I then started to get greyish discharge with black specks, burning, and cystitis feelings. I feel right back to square 1 with my symptoms, which were improving with Vagifem. I’m terrified about what I’ve done to my insides!"