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Allopurinol User Reviews & Ratings (Page 3)

Brand names: Zyloprim, Aloprim

Allopurinol has an average rating of 7.4 out of 10 from a total of 91 reviews on Drugs.com. 64% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Allopurinol

Commonly mentioned side effects
  • Anonymous
  • April 3, 2012

For Gout "Allopurinol works extremely well for me. I am on 300 mg per day, and it seems to do the trick. However, my one beef is that sometimes the pills will suddenly stop working, and I have to buy a new batch. I am guessing this is because of humidity changes or temperature changes, but it is annoying. For example, about half the times I fly somewhere, I find on my arrival that the pills stop working; I carry the pills in my pocket or in my carry-on while in the plane, but even so, they stop functioning. I am guessing it is the change in humidity, but who knows?"

9 / 10
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  • Zee...
  • May 29, 2017

For Gout "At the age of sixty, I've dealt with gout 3 to 5 times a year for about ten years. I never take it until I have a flare-up. Having an aversion to meds of any kind, I sometimes wait for a week or two, enduring debilitating pain, before I begin titration of allopurinol. It always goes away within a few days. I used to wonder if it was coincidence that it subsided after I take it. After having around 30 bouts with gout, I'm convinced this drug works very well for me."

10 / 10
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26 Report
  • Gou...
  • Taken for 6 months to 1 year
  • May 9, 2017

For Gout "Like all meds, this does not work for everyone, and I'm unlucky. I still get gout symptoms (inflamed big toe joint, pain) after using it. Almost a year on this med, and 5.7 uric acid level down from 5.8."

1 / 10
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24 Report
  • Jol...
  • Taken for less than 1 month
  • February 22, 2022

For Gout "Being lactose intolerant, I had to request a liquid version, which is off-license. The absorption rate is faster. After only a week, I suffered nosebleeds, headaches, and bowel problems. My GP is dismissive and doesn't see a connection. Anyone had similar issues?"

5 / 10
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  • jul...
  • Taken for 1 to 6 months
  • July 25, 2023

For Gout "Started taking Allopurinol for gout (I'm 68) with naproxen. I stopped the Naproxen, continued with Allopurinol and felt pretty good, little or no pain anywhere. A month later, I had another blood test and the GP called to say my uric acid level was (still) too high and told me to double the dose. Here's the thing: On taking the double dose (200mg), light gout symptoms and an RSI type pain in both wrists, and an old neck pain returned. I treated these with Naproxen and the pain went away, however, when I stopped taking Naproxen (as it's hard on the stomach), the wrist weakness and very minor gout pain returned. So the Allopurinol (for me) exacerbated pain symptoms anywhere in the body in the short 3-week term. There's a research project in this."

7 / 10
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  • JFa...
  • May 10, 2020

For Gout "Been taking allopurinol for 6 months and have had more frequent gout attacks than before. Uric acid levels not lowered. Only impact really seems to have been a few negative side effects. Seriously, this is the best medicine can provide for this condition in 2020? Oh, yeah, I guess a few of our illusions have been undone there lately."

2 / 10
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  • Sli...
  • Taken for 1 to 6 months
  • December 6, 2019

For Gout "Have taken allopurinol for four weeks and have totally lost my sex drive and now have ED (erectile dysfunction). This was six months ago, and there is no change. I would not recommend this unless you want to be chemically castrated."

1 / 10
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  • Anonymous
  • October 25, 2023

For Gout "Started taking allopurinol at age 54 after trying to manage gout through lifestyle and diet for 14 years. Adopted a vegetarian diet, limited use of alcohol, and was not overweight. What finally 'cracked' me was a severe attack in one of my ankles, whereas previous attacks (about 1/year) always struck the left toe joint. Attacks were typically prompted by severe exertion and dehydration. The uric acid level had crept up to 7.2 and stayed there. Started on a regimen of 300mg allopurinol and 10mg colchicine. It prompted an initial minor flare-up, but none since. Stopped the colchicine after 6 months and am continuing the allopurinol 300mg once daily. The most recent uric acid level is 5.2 and has had no issues or side effects."

10 / 10
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  • Woo...
  • Taken for 5 to 10 years
  • November 20, 2022

For Gout "Been taking allopurinol for years. Dr. didn't really tell me the side effects. It works well on my gout, but allopurinol has given me erectile dysfunction and a low to nil libido. They don't tell you that, you have to dig around on the internet to find that out. I'll be looking for an alternative."

2 / 10
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  • Vij...
  • July 23, 2015

For Gout "Tried allopurinol low dose one day after the gout attack. It increased my uric acid to 12 from 8 (measured reliably). Dr. said it will take a week to stabilize, but I guess I am one of the unlucky guys."

1 / 10
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31 Report
  • Col...
  • Taken for 1 to 6 months
  • September 21, 2020

For Gout "Expat living in rural Philippines (jungle), there's not many options for health care, and because of COVID, it's difficult to get treatment for gout. I started getting severe pain in my finger joints and what I now know is tophi. I had high uric acid levels when I got tested a year earlier, so I concluded I have gout. Online, I read research papers that explained the mechanism of uric acid saturation and the formation of uric acid crystals that cause gout. I started taking allopurinol at 100 mg and over several weeks increased to 500 mg/day. I know that I will still have joint pain in the short term as uric acid crystals dissolve. My uric acid levels are down to 6 mg/ml as read on my home tester. I plan on reducing meds gradually in a couple of years once the tophi has gone... To date, no side effects and no loss of sex drive."

10 / 10
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  • Gri...
  • Taken for 1 to 2 years
  • November 30, 2020

For Gout "Have been taking Allopurinol 100 mg but have had three attacks of gout over the past three months and five attacks in the past eleven months. Each of these attacks has been treated with a five-day course of Colchicine."

2 / 10
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  • sna...
  • Taken for 1 to 2 years
  • August 24, 2020

For Gout "UK man here, 48 years old. At the age of 32, I went to the hospital believing I'd broken bones in my foot. I hobbled in, told by the doctor, 'Nah, you got gout, you need to rest that foot and make a go appointment.' I didn't because the pain subsided. Then followed intermittent gout attacks every 2 or 3 years. I had to get it sorted after a really bad attack where I couldn't even get out of bed, and going up and down stairs was traumatic. Prescribed 2x100mg Allopurinol and Omeprazole. This after having a go with Colchicine, which I rejected graphically. Allopurinol is a true wonder drug. I've never been on medication before, so I can only tell you it does exactly what it says on the tin. Not only that, it's cheaply manufactured. I don't smoke, don't drink, and am of healthy weight, so I must conclude my condition is hereditary."

10 / 10
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  • Che...
  • Taken for 2 to 5 years
  • July 10, 2018

For Urinary Tract Stones "I am taking allopurinol 300 mg/day to prevent uric acid kidney stones. I commenced taking them in Nov. 2017 after many years of regular stones forming, however, since this date, I have had no reoccurrence of stones. I have started having a salty type taste in my mouth, which I put down to the medication, however, this is a small price to pay for the relief from passing kidney stones."

9 / 10
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  • Anonymous
  • October 8, 2020

For Gout "I had terrible pain for years. Followed the fad and gave up meat. Gout got no better. Then tried allopurinol, within three months, I was pain-free for the first time in ten years. I even started eating meat again, still pain-free, so it's great."

9 / 10
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  • Hon...
  • Taken for 10 years or more
  • November 1, 2019

For Gout "Have been on 300 mcg of allopurinol every day for approximately 30 years, and suddenly last week I had a gout attack. I am in a quandary as to why. My doctor doesn't seem to come up with an answer. I am wondering whether it is worth it to keep doing this if it isn't going to stop gout attacks."

5 / 10
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  • Sim...
  • Taken for 1 to 6 months
  • September 10, 2022

For Gout "Excellent so far. I am a 57-year-old male, and my last major flare-up was when I was 40, which was awful. I couldn’t walk, even driving was difficult as pressing down the clutch caused pain. Over the last 17 years, I have been relatively pain-free, and then suddenly, three years ago, it came back. Then recently, I have had minor flare-ups, so Doc recommended allopurinol, and all great so far…although I have switched to a veg diet once per day."

10 / 10
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  • Owd...
  • Taken for 1 to 2 years
  • July 17, 2024

For Gout "68 years old male, suffered gout for years mainly in my big toe. Intense pain, couldn’t get out of bed. I used to fight it with Naproxen, which I used to take at the onset of an attack. If I took it early enough, it would head the full-blown attack off at the pass. My doctor put me on Allopurinol, which I was not happy about, seeing all the possible side effects. Started with 100mg, then increased to 200mg a day as I was still getting attacks. Been using it for 12 months or so now, still get the odd attack, and after having a normal healthy sex life, I have developed a low libido and erectile dysfunction that even Viagra cannot assist with. From reviews, I see others have suffered this. I am going to come off the drug to test my theory. I also suffer fatigue, which was never me, my get-up-and-go seems to have got up and gone. I will see what the results of my Allopurinol absence bring before consulting with my GP."

6 / 10
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  • fri...
  • December 26, 2009

For Urinary Tract Stones "I have just started to use this drug, and I hope it works. I have had more than four lithotripsy operations so far: three external and one internal. I've got to do something, it's destroying my kidneys and my pocketbook. I'll try to keep my fellow sufferers up to date."

7 / 10
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  • Kat...
  • Taken for 1 to 6 months
  • March 29, 2021

For Gout "Get rash on one leg only, but it itches so bad I've bled with scratching. I now wear an exfoliating glove before scratching because it drives me crazy. Can't cover with a dressing because the heat becomes so intense. It's a red pinhead rash, is it a side effect of allopurinol? Drives me nuts."

3 / 10
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  • Soo...
  • January 1, 2016

For Urinary Tract Stones "I have been on 300 mg Allopurinol daily for 7-8 years to control kidney stones. My experience has been very satisfactory. The pill color was orange for all the years until my last refill. I get a 90-count refill, and the last two refills have been white with the imprint AX and without any numerals. I have not unsealed the last one of those two refills, as I have a few left in the first one. However, I have been having a pain in my left side that I finally have determined is a kidney stone symptom. In recent reflection, I believe this has started within the period when I began with the white AX pills. Would appreciate your comments. I do intend to consult my local pharmacist this coming week."

9 / 10
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  • Lor...
  • Taken for 5 to 10 years
  • January 21, 2023

For Gout "I was diagnosed with gout in my toe when I was 18 years of age. I was advised by my doctor to drink plenty of water and eat a healthy diet, which I was already doing. As I have gotten older, the flare-ups of gout have increased, and I was recently prescribed allopurinol, which has helped a lot."

10 / 10
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  • Gou...
  • February 18, 2017

For Gout "300 mg and Colchicine to reduce anything that might happen. Miracle drug if something on the sideline whoops the gout in shape. Took for 30 days and was in perfect shape... had a bad gout attack and found more Colchicine, which was prescribed a year ago and I wasn't supposed to be taking... anyways, however, I was taking it for 30 more days... My feet were in peace and in heaven for the ultimate use of your foot in the way you wanted. 3 days after Colchicine ran out... It's been hell! I don't know what to do... I just might finally cut my foot off!"

3 / 10
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  • big...
  • Taken for 1 to 2 years
  • April 2, 2025

"Taking allopurinol for over a year. Because of recurring gout flares and my first kidney stone attack. My feet and legs began to swell. Doctor suggested we stop the allopurinol to see if swelling would subside. After 5 days, all swelling was gone. Now, 6 months off allopurinol. Gout flares have returned. Considering next steps."

8 / 10
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  • R C...
  • Taken for 1 to 6 months
  • October 6, 2024

For Gout "I’m 67 years old and have had gout several times in the past 10-15 years, mainly in my big toe and once in my right knee (very painful) and misdiagnosed by my GP! Back in July of this year, I went to a podiatrist for a pain in my second toe. He tested my uric acid level and said it was almost a 10. Advised me to try allopurinol, of which my nephrologist agreed that my kidneys would benefit from a lower uric acid level as well. Started taking 300 mg, and after about a month, my levels were down to approximately 4+. Side effects: low energy, foot pain/swollen sole, mainly on one foot. I’ve been hobbling around for several weeks now! I think I’ll try skipping a few doses and see if that helps? I may also try a lower dosage too! On the positive side: it lowered my uric acid levels, which is a major plus!"

8 / 10
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