Serum Free Light Chain Testing
Medically reviewed by Drugs.com. Last updated on Apr 6, 2025.
AMBULATORY CARE:
What you need to know about serum free light chain (SFLC) testing:
SFLC testing is a blood test that measures light chains (proteins) in your blood. This test may be done if you have risk factors for a blood cell or autoimmune disorder. Examples include multiple myeloma, amyloidosis, and lupus. The test results may be used to help diagnose a condition or to check how well treatment is working.
How to prepare for SFLC testing:
You do not need to prepare anything for an SFLC blood test. You can eat and drink as usual. Wear a short-sleeved or loose shirt to the test. This will make it easier to draw your blood.
What to expect after SFLC testing:
- You may have pain or a bruise where the blood was drawn. The pain and bruise should go away within a few days.
- Your healthcare provider will tell you when and how to get your test results. Your provider will tell you what your results mean.
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Risks of SFLC testing:
Certain health conditions may affect the test results. An example is chronic kidney disease. SFLC testing must be used along with other tests or scans to diagnose a condition. You may need more than 1 SFLC test to monitor a confirmed health condition.
Call your doctor if:
- You have new or increasing pain or bruising where the blood was drawn.
- You have questions or concerns about your condition or care.
Follow up with your doctor as directed:
You may get your blood test results when you follow up with your doctor. Write down your questions so you remember to ask them during your visits.
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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.
Further information
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