Diabetic Ketoacidosis
Medically reviewed by Drugs.com. Last updated on Apr 6, 2025.
Diabetic ketoacidosis (DKA) is a life-threatening condition caused by dangerously high blood sugar levels. Your blood sugar levels become high because your body does not have enough insulin. Insulin helps move sugar out of the blood so it can be used for energy. The lack of insulin forces your body to use fat instead of sugar for energy. As fats are broken down, they leave chemicals called ketones that build up in your blood. Ketones are dangerous at high levels.
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An IV
is a small tube placed in your vein that is used to give you medicine or liquids.
You may need extra oxygen
if your blood oxygen level is lower than it should be. You may get oxygen through a mask placed over your nose and mouth or through small tubes placed in your nostrils. Ask your healthcare provider before you take off the mask or oxygen tubing.
Monitoring:
Your weight may be measured each day to monitor dehydration. Healthcare providers compare your weight from day to day to record how much body fluid you have. You may also need any of the following:
- A heart monitor is an EKG that stays on continuously to record your heart's electrical activity.
- A pulse oximeter is a device that measures the amount of oxygen in your blood. A cord with a clip or sticky strip is placed on your finger, ear, or toe. The other end of the cord is hooked to a machine.
- Intake and output may be measured. Healthcare providers will keep track of the amount of liquid you are getting. They also may need to know how much you are urinating. Ask healthcare providers if they need to measure or collect your urine.
- Neuro signs , or neuro checks show healthcare providers your brain function. They will check how your pupils react to light. They may check your memory and how easily you wake up. Your hand grasp and balance may also be tested.
Drugs used to treat this and similar conditions
Humulin R
Humulin R is a man-made insulin that is used to control high blood sugar in adults and children ...
Humalog
Humalog (insulin lispro) is used to treat type 1 (insulin-dependent) diabetes in adults. Includes ...
Benlysta
Benlysta infusion is used to treat active systemic lupus erythematosus (SLE) and active lupus ...
Novolin R
Novolin R is used for diabetes, type 1, diabetic ketoacidosis, gestational diabetes, growth hormone ...
Novolog
NovoLog is a fast-acting insulin used to treat diabetes to control blood sugar levels in adults and ...
NovoLog FlexPen
NovoLog FlexPen is used for diabetes, type 1, diabetic ketoacidosis, nonketotic hyperosmolar ...
Apidra
Apidra is used to treat type 1 (insulin-dependent) diabetes in adults. Learn about side effects ...
NovoLog PenFill
NovoLog PenFill is used for diabetes, type 1, diabetic ketoacidosis, nonketotic hyperosmolar ...
Insulin glulisine
Insulin glulisine systemic is used for diabetes, type 1, diabetic ketoacidosis, nonketotic ...
Insulin aspart
Insulin aspart systemic is used for diabetes, type 1, diabetic ketoacidosis, nonketotic ...
Medicines:
- IV liquids help treat dehydration. Electrolytes may be added to the fluids to replace what has been lost from your body.
- Insulin decreases the amount of sugar in your blood. You may need to take insulin until your blood sugar level returns to a safe level.
- Glucose may be needed when your blood sugar level begins to decrease. This is to prevent your blood sugar level from dropping too quickly while you are getting insulin.
- Potassium may be given if your blood levels of potassium are low. This can happen when large amounts of insulin are given.
Tests:
- Blood and urine tests will show your ketone and blood sugar levels. They will also show if you are dehydrated or have an infection.
- An arterial blood gas (ABG) test measures the amount of oxygen and carbon dioxide in your blood.
- A chest x-ray may show signs of infection.
- An EKG test records your heart rhythm and how fast your heart beats.
Treatment:
- A Foley catheter is a tube put into your bladder to drain urine into a bag. This allows your healthcare provider to measure your urine. Keep the bag below your waist. This will prevent urine from flowing back into your bladder and causing an infection or other problems. Also, keep the tube free of kinks so the urine will drain properly. Do not pull on the catheter. This can cause pain and bleeding, and may cause the catheter to come out.
- A nasogastric (NG) tube helps remove fluid from your stomach. The NG tube is also used to give you medicines or liquids if you cannot swallow. The NG tube is put down your nose and into your stomach.
- An arterial line is a tube that is placed into an artery (blood vessel), usually in the wrist or groin. An arterial line may be used for measuring your blood pressure or for taking blood.
- A ventilator is a machine that gives you oxygen and breathes for you when you cannot breathe well on your own. An endotracheal (ET) tube is put into your mouth or nose and attached to the ventilator. You may need a trach if an ET tube cannot be placed. A trach is a tube put through an incision and into your windpipe.
Treatment options
The following list of medications are related to or used in the treatment of this condition.
Diabetes education:
Healthcare providers will teach you how to manage your diabetes.
- How to check your blood sugar level: You will learn what your blood sugar level should be. You will be given information on when to check your blood sugar level. You will learn what to do if your level is too high or too low. Write down the times of your checks and your levels. Take them to all follow-up appointments.
- About insulin: You and your family members will be taught how to draw up and give insulin. You will learn how much insulin you need and what time to inject insulin. You will be taught when to not give insulin. Your provider will also teach you how to dispose of needles and syringes.
- About nutrition: A dietitian will help you make a meal plan to keep your blood sugar level steady. You will learn how food affects your blood sugar levels. You will also learn to keep track of sugar and starchy foods (carbohydrates). Do not skip meals. Your blood sugar level may drop too low if you have taken insulin and do not eat.
- Exercise and diabetes: You will learn why physical activity is important. You and your provider will make a plan for your activity. Your provider will tell you what a healthy weight will be for you. He or she will help you make a plan to get to that weight and stay there.
RISKS:
You may develop severe dehydration. This can cause abnormal heartbeats. Blood flow may be decreased and cause organ failure. Decreased blood flow to your brain may lead to seizures, swelling, or a coma. Treatment may cause your blood sugar level to become too low. Very low blood sugar levels may cause seizures, or you may become unconscious. Too much fluid replacement may cause trouble breathing or cerebral edema (water around the brain). DKA can be life-threatening.
CARE AGREEMENT:
You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your healthcare providers to decide what care you want to receive. You always have the right to refuse treatment.© Copyright Merative 2025 Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.
Learn more about Diabetic Ketoacidosis
Treatment options
- Medications for Diabetic Ketoacidosis
- Medications for Diabetic Ketoacidosis, in DM Type I
- Medications for Diabetic Ketoacidosis, in DM Type II
Care guides
Symptoms and treatments
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.