Generic Name: Lesinurad (le SIN ure ad)
Brand Name: Zurampic
Medically reviewed by Drugs.com. Last updated on Jul 16, 2020.
- Kidney problems like kidney failure have happened with Zurampic (lesinurad). This was more common in people who took Zurampic (lesinurad) without certain other drugs. This medicine must be taken along with either allopurinol or febuxostat. Talk with your doctor.
The Zurampic brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Uses of Zurampic:
- It is used to lower uric acid in the blood.
What do I need to tell my doctor BEFORE I take Zurampic?
- If you are allergic to Zurampic (lesinurad); any part of Zurampic (lesinurad); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have kidney disease or are on dialysis.
- If you have had a kidney transplant.
- If you have any of these health problems: Lesch-Nyhan syndrome or tumor lysis syndrome (TLS).
- If you are taking any of these drugs: Divalproex or valproic acid.
This is not a list of all drugs or health problems that interact with Zurampic (lesinurad).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Zurampic (lesinurad) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Zurampic?
- Tell all of your health care providers that you take Zurampic (lesinurad). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You may have more gout attacks after you first start taking Zurampic (lesinurad). Do not stop taking Zurampic (lesinurad). You may be given other drugs to keep you from having these gout attacks. Talk with your doctor.
- Very bad heart problems like heart attack and stroke have happened with Zurampic (lesinurad). Sometimes, these heart problems were deadly. It is not known if Zurampic (lesinurad) is what caused these effects. Talk with the doctor.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking Zurampic (lesinurad).
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Zurampic (lesinurad) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Zurampic) best taken?
Use Zurampic (lesinurad) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take in the morning.
- Take with food.
- Take with a full glass of water.
- Take Zurampic (lesinurad) at the same time as the drug you take it with. Do not take Zurampic (lesinurad) by itself. Tell your doctor if you stop taking the other drug for any reason.
- Drink lots of noncaffeine liquids every day unless told to drink less liquid by your doctor.
What do I do if I miss a dose?
- Skip the missed dose and go back to your normal time.
- Do not take more than 1 dose of Zurampic (lesinurad) in the same day.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Upset stomach or throwing up.
- Lower back or side pain.
- Chest pain or pressure.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
What are some other side effects of Zurampic?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
How do I store and/or throw out Zurampic?
- Store at room temperature.
- Protect from light.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Zurampic (lesinurad), please talk with your doctor, nurse, pharmacist, or other health care provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Zurampic (lesinurad)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- En Español
- 2 Reviews
- Drug class: antihyperuricemic agents
- FDA Approval History