Generic Name: von Willebrand Factor (Recombinant) (von WILL le brand FAK tor ree KOM be nant)
Brand Name: Vonvendi
Uses of Vonvendi:
- It is used to treat von Willebrand disease.
- It is used to stop bleeding.
What do I need to tell my doctor BEFORE I take Vonvendi?
- If you have an allergy to Vonvendi (von willebrand factor (recombinant)) or any part of this medicine.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have an allergy to hamster or mouse protein.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Vonvendi with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Vonvendi?
- Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
- Allergic side effects may rarely happen.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Blood clots have happened with Vonvendi. Tell your doctor if you have ever had a blood clot. Talk with your doctor.
- Call the doctor right away if the normal dose does not work as well.
- Talk with the doctor before you travel. You will need to bring enough of this medicine for use during travel.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Vonvendi while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Vonvendi) best taken?
Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a vein.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Follow how to use as you have been told by the doctor or read the package insert.
- Wash your hands before and after use.
- This medicine needs to be mixed before use. Follow how to mix as you were told by the doctor.
- If stored in a refrigerator, let Vonvendi come to room temperature before mixing. Do not heat this medicine.
- Do not shake.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- After mixing, do not refrigerate.
- Use within 3 hours of making.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Dizziness or passing out.
- Very bad headache.
- A burning, numbness, or tingling feeling that is not normal.
- Upset stomach or throwing up.
- Feeling very tired or weak.
- A fast heartbeat.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.
What are some other side effects of Vonvendi?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Vonvendi?
- Store in a refrigerator. Do not freeze.
- If needed, you may store at room temperature.
- If stored at room temperature, make a note of the date it was placed at room temperature.
- If stored at room temperature, throw away any unused vials after 12 months or after the expiration date, whichever comes first.
- Do not put Vonvendi back in the refrigerator after it has been stored at room temperature.
- Store in original container.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
Disclaimer: This information should not be used to decide whether or not to take Vonvendi or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Vonvendi (von willebrand factor (recombinant)). This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
Review Date: February 7, 2018
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- Drug class: miscellaneous coagulation modifiers