Generic Name: Panitumumab (pan i TOOM yoo mab)
Brand Name: Vectibix
- Skin problems like acne, itching, redness, rash, and dry or cracked skin are common with Vectibix (panitumumab). Very bad skin problems, infections, and tissue damage have also happened with this medicine. Sometimes these have been life-threatening or deadly. Talk to your doctor about any skin changes you may have.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
Uses of Vectibix:
- It is used to treat colorectal cancer.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Vectibix?
- If you have an allergy to panitumumab or any other part of Vectibix.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have a certain gene mutation (RAS) or if you do not know if you have this type of gene mutation.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Vectibix?
- Tell all of your health care providers that you take Vectibix. This includes your doctors, nurses, pharmacists, and dentists.
- If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have an eye exam as you have been told by your doctor.
- Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects from the sun while taking this medicine and for at least 2 months after care ends.
- Very bad and sometimes deadly side effects have happened during the infusion. Tell your doctor if you have any bad effects during the infusion.
- Very bad loose stools (diarrhea) and fluid loss (dehydration) have happened with Vectibix when used with chemo drugs. This can lead to kidney problems or other health problems. Talk with your doctor.
- Blood clots have happened with this medicine. Sometimes, these blood clots have been deadly. Talk with the doctor.
- People with a certain gene mutation (RAS) may not benefit from Vectibix. Their tumor may also get worse and chance of death may be raised. Talk with the doctor.
- If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during care and for 6 months after care ends. Use birth control that you can trust.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- Use birth control that you can trust during care and for 6 months after care ends.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Vectibix) best taken?
Use Vectibix as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of low magnesium levels like mood changes, muscle pain or weakness, muscle cramps or spasms, seizures, shakiness, not hungry, very bad upset stomach or throwing up, or a heartbeat that does not feel normal.
- Very upset stomach or throwing up.
- Very loose stools (diarrhea).
- Change in eyesight, eye pain, or very bad eye irritation.
- Not able to pass urine or change in how much urine is passed.
- Chest pain or pressure.
- Coughing up blood.
- Dry mouth.
- Mouth irritation or mouth sores.
- Redness or swelling where the shot is given.
- Very hard stools (constipation).
- Feeling very tired or weak.
- Swelling in hands or feet.
- Change in skin or finger nails.
- Very bad and sometimes deadly lung problems have happened with this medicine. Call your doctor right away if you have lung or breathing problems like trouble breathing, shortness of breath, or a cough that is new or worse.
What are some other side effects of Vectibix?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Eye irritation.
- Feeling tired or weak.
- Belly pain.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Eyelash growth.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Vectibix?
- If you need to store Vectibix at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take Vectibix (panitumumab) or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Vectibix. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
Review Date: September 6, 2017
More about Vectibix (panitumumab)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 1 Review – Add your own review/rating
- Drug class: EGFR inhibitors