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Phenylephrine and ketorolac

Generic Name: phenylephrine and ketorolac (fen-il-EF-rin and KEE-toe-ROLE-ak)
Brand Name: Omidria

Phenylephrine and ketorolac is used for:

Maintaining pupil size during cataract surgery. It is also used to reduce eye pain after eye surgery. It may also be used for other conditions as determined by your doctor.

Phenylephrine and ketorolac is a mydriatic and nonsteroidal anti-inflammatory drug (NSAID) combination. The mydriatic works on your iris (muscle in your eye) to widen the pupil. The NSAID works by blocking the production of prostaglandin, a substance that causes pain.

Do NOT use phenylephrine and ketorolac if:

  • you are allergic to any ingredient in phenylephrine and ketorolac
  • you are in your last trimester of pregnancy

Contact your doctor or health care provider right away if any of these apply to you.

Before using phenylephrine and ketorolac:

Some medical conditions may interact with phenylephrine and ketorolac. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines (eg, aspirin or other NSAIDs, such as ibuprofen), foods, or other substances

Some MEDICINES MAY INTERACT with phenylephrine and ketorolac. However, no specific interactions with phenylephrine and ketorolac are known at this time.

Ask your health care provider if phenylephrine and ketorolac may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use phenylephrine and ketorolac:

Use phenylephrine and ketorolac as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Phenylephrine and ketorolac is for use in the eye only.
  • Phenylephrine and ketorolac is given as an eye rinse at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
  • If you miss a dose of phenylephrine and ketorolac, call your doctor to find out what to do.

Ask your health care provider any questions you may have about how to use phenylephrine and ketorolac.

Important safety information:

  • Tell your doctor or dentist that you take phenylephrine and ketorolac before you receive any medical or dental care, emergency care, or surgery.
  • Bright lights may bother your eyes. It may help to wear sunglasses.
  • Lab tests, including blood pressure, may be performed while you use phenylephrine and ketorolac. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using phenylephrine and ketorolac while you are pregnant. If you are or will be breast-feeding while you use phenylephrine and ketorolac, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of phenylephrine and ketorolac:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Eye irritation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe eye irritation; severe or persistent dizziness or headache.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of phenylephrine and ketorolac:

Phenylephrine and ketorolac is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

General information:

  • If you have any questions about phenylephrine and ketorolac, please talk with your doctor, pharmacist, or other health care provider.
  • Phenylephrine and ketorolac is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take phenylephrine and ketorolac or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about phenylephrine and ketorolac. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to phenylephrine and ketorolac. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using phenylephrine and ketorolac.

Review Date: August 8, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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