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Balanced Salt Solution (intraocular)

Generic name: ophthalmic irrigation (intraocular) [ off-THAL-mik-ir-i-GAE-tion ]
Brand names: Balanced Salt Solution, BSS, BSS Plus, Endosol Extra intraocular
Drug class: Ophthalmic lubricants and irrigations

Medically reviewed by on Aug 7, 2023. Written by Cerner Multum.

What is intraocular Balanced Salt Solution?

Intraocular ophthalmic (inside the eye) irrigation is a sterile cleansing solution.

Intraocular Balanced Salt Solution is used to maintain the natural condition of the eye during a surgical procedure such as cataract surgery.

Intraocular Balanced Salt Solution may also be used for purposes not listed in this medication guide.

Intraocular Balanced Salt Solution side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Balanced Salt Solution may cause serious side effects. Call your doctor at once if you have:

Common side effects of Balanced Salt Solution may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


After surgery, call your doctor if you have vision problems, eye pain or redness, or increased sensitivity to light.

Before taking this medicine

To make sure intraocular Balanced Salt Solution is safe for you, tell your doctor if you have:

It is not known whether intraocular Balanced Salt Solution will harm an unborn baby. Tell your doctor if you are pregnant.

It is not known whether intraocular ophthalmic irrigation passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How is intraocular Balanced Salt Solution given?

Intraocular Balanced Salt Solution is injected into the eye during surgery. A healthcare provider will give you this injection.

What happens if I miss a dose?

Because you will receive intraocular Balanced Salt Solution in a surgical setting, you are not likely to miss a dose.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while after receiving intraocular Balanced Salt Solution?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect intraocular Balanced Salt Solution?

It is not likely that other drugs you take orally or inject will have an effect on intraocular Balanced Salt Solution used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

More about Balanced Salt Solution (ophthalmic irrigation, intraocular ophthalmic)

Patient resources

Other brands

BSS, BSS Plus, Endosol Extra, Navstel

Professional resources

Related treatment guides

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.